Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Hacettepe University, Ankara, Turkey
Turk J Med Sci. 2021 Apr 30;51(2):393-399. doi: 10.3906/sag-2005-315.
Vertebral compression fracture is a hallmark of osteoporosis (OP) and by far the most prevalent fragility fracture. It is well proven that patients who develop a vertebral compression fracture are at substantial risk for additional fractures. Diagnosis is based on adequate clinical evaluation, imaging, and laboratory tests. The imaging of OP and fragility fractures includes conventional radiology to evaluate spinal fractures, bone mineral density (BMD) testing by dual energy x-ray densitometry, quantitative computerized tomography, magnetic resonance imaging, bone scintigraphy (if necessary), and ultrasound. Screening and treatment of individuals with high risk of osteoporotic fracture are cost-effective, but approximately two-thirds of the vertebral compression fractures (VCF) that occur each year are not accurately diagnosed and, therefore, not treated. Evaluation of VCFs, even though they may be asymptomatic, seems essential to health-related and/or clinical research on OP.
椎体压缩性骨折是骨质疏松症（OP）的一个标志，也是迄今为止最常见的脆性骨折。已有充分证据表明，发生椎体压缩性骨折的患者存在发生其他骨折的巨大风险。诊断基于充分的临床评估、影像学和实验室检查。OP 和脆性骨折的影像学检查包括常规放射学评估脊柱骨折、双能 X 线骨密度测定、定量计算机断层扫描、磁共振成像、骨闪烁成像（如有必要）和超声。对骨质疏松性骨折高危人群进行筛查和治疗具有成本效益，但每年发生的大约三分之二的椎体压缩性骨折（VCF）并未得到准确诊断，因此也未得到治疗。即使 VCF 可能无症状，对其进行评估似乎对 OP 的与健康相关和/或临床研究也至关重要。
