• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

采用髓芯减压联合植骨及多孔钽棒植入术修复非创伤性股骨头坏死

Repair of non-traumatic femoral head necrosis by marrow core decompression with bone grafting and porous tantalum rod implantation.

作者信息

Peng Keyun, Wang Yu, Zhu Jifeng, Li Chengling, Wang Ziming

机构信息

Keyun Peng, Orthopedic Central Joint and Limb Surgery, Army Medical Center of PLA (Daping Hospital), Army Medical University, Yuzhong District, Chongqing, China.

Yu Wang, Orthopedic Central Joint and Limb Surgery, Army Medical Center of PLA (Daping Hospital), Army Medical University, Yuzhong District, Chongqing, China.

出版信息

Pak J Med Sci. 2020 Sep-Oct;36(6):1392-1396. doi: 10.12669/pjms.36.6.2176.

DOI:10.12669/pjms.36.6.2176
PMID:32968415
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7501027/
Abstract

OBJECTIVE

To compare the clinical effects of marrow core decompression with bone grafting and marrow core decompression with porous tantalum rod implantation in treating avascular necrosis of non-traumatic femoral head.

METHODS

This prospective study selected 60 patients (74 hips) with avascular necrosis of femoral head admitted to Daping Hospital from January 2018 to March 2019. According to treatment methods, the 60 patients were randomly divided into two groups, i.e. 30 patients in one group were treated by marrow core decompression with bone grafting, and the other 30 patients in the other group were treated with marrow core decompression and porous tantalum rod implantation.

RESULTS

All implantation treatments were successful. No significant difference was found in surgical duration, hemorrhage volume and duration of hospitalization stay between the two groups during follow-up. All Harris scores were significantly improved (P<0.05) following treatment compared to those before treatment. The Harris score of patients treated with porous tantalum rod implantation was higher than that of patients treated with bone grafting (P<0.05) after 12 months following treatment and such a difference was significant.

CONCLUSION

The combination of marrow core decompression and porous tantalum rod implantation can better improve the functions of hip joints with early femoral head necrosis than marrow core decompression with bone grafting, and can also prevent articular cartilage from collapsing gradually.

摘要

目的

比较髓芯减压植骨术与髓芯减压联合多孔钽棒植入术治疗非创伤性股骨头缺血性坏死的临床效果。

方法

本前瞻性研究选取2018年1月至2019年3月在大坪医院收治的60例（74髋）股骨头缺血性坏死患者。根据治疗方法，将60例患者随机分为两组，一组30例采用髓芯减压植骨术治疗，另一组30例采用髓芯减压联合多孔钽棒植入术治疗。

结果

所有植入治疗均成功。随访期间两组手术时间、出血量及住院时间差异无统计学意义。与治疗前相比，治疗后所有患者的Harris评分均显著提高（P<0.05）。治疗后12个月，多孔钽棒植入术治疗患者的Harris评分高于植骨术治疗患者（P<0.05），且差异有统计学意义。

结论

与髓芯减压植骨术相比，髓芯减压联合多孔钽棒植入术能更好地改善早期股骨头坏死髋关节的功能，还能防止关节软骨逐渐塌陷。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/202b/7501027/e25d4142075f/PJMS-36-1392-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/202b/7501027/e25d4142075f/PJMS-36-1392-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/202b/7501027/e25d4142075f/PJMS-36-1392-g001.jpg

相似文献

1
Repair of non-traumatic femoral head necrosis by marrow core decompression with bone grafting and porous tantalum rod implantation.采用髓芯减压联合植骨及多孔钽棒植入术修复非创伤性股骨头坏死
Pak J Med Sci. 2020 Sep-Oct;36(6):1392-1396. doi: 10.12669/pjms.36.6.2176.
2
[Treatment of avascular necrosis of the femoral head by lesions clearance, compact bone grafting, and porous tantalum rod implantation].[病灶清除、致密骨移植及多孔钽棒植入治疗股骨头缺血性坏死]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2011 Nov;25(11):1335-8.
3
[Comparison of core decompression with stem cell transplantation and tantalum rod implanting in treating stage II non-traumatic osteonecrosis of femoral head].[髓芯减压术与干细胞移植及钽棒植入术治疗Ⅱ期非创伤性股骨头坏死的比较]
Zhongguo Gu Shang. 2016 Dec 25;29(12):1119-1124. doi: 10.3969/j.issn.1003-0034.2016.12.011.
4
Tantalum rod implantation for femoral head osteonecrosis: survivorship analysis and determination of prognostic factors for total hip arthroplasty.钽棒植入治疗股骨头坏死：全髋关节置换术的生存率分析及预后因素的确定
Int Orthop. 2016 Jul;40(7):1397-407. doi: 10.1007/s00264-015-2897-1. Epub 2015 Aug 11.
5
Comparison of core decompression and porous tantalum rod implantation with conservative treatment for avascular necrosis of the femoral head: A minimum 18 month follow-up study.股骨头缺血性坏死的髓芯减压与多孔钽棒植入术与保守治疗的比较：一项至少18个月的随访研究。
Exp Ther Med. 2020 Jul;20(1):472-478. doi: 10.3892/etm.2020.8669. Epub 2020 Apr 21.
6
Effect of Osteonecrosis Intervention Rod Versus Core Decompression Using Multiple Small Drill Holes on Early Stages of Necrosis of the Femoral Head: A Prospective Study on a Series of 60 Patients with a Minimum 1-Year-Follow-Up.骨坏死干预棒与多小孔髓芯减压术对早期股骨头坏死的疗效：一项对60例患者进行至少1年随访的前瞻性研究
Open Orthop J. 2015 May 15;9:179-84. doi: 10.2174/1874325001509010179. eCollection 2015.
7
Survivorship analysis and radiographic outcome following tantalum rod insertion for osteonecrosis of the femoral head.钽棒植入治疗股骨头坏死的生存分析及影像学结果
J Bone Joint Surg Am. 2006 Nov;88 Suppl 3:48-55. doi: 10.2106/JBJS.F.00538.
8
Combining autologous bone marrow buffy coat and angioconductive bioceramic rod grafting with advanced core decompression improves short-term outcomes in early avascular necrosis of the femoral head: a prospective, randomized, comparative study.联合自体骨髓血运重建与高级髓芯减压术治疗早期股骨头坏死：前瞻性随机对照研究
Stem Cell Res Ther. 2021 Jun 19;12(1):354. doi: 10.1186/s13287-021-02436-0.
9
Effect of a porous tantalum rod on early and intermediate stages of necrosis of the femoral head.多孔钽棒对股骨头坏死早中期的影响。
Biomed Mater. 2010 Dec;5(6):065003. doi: 10.1088/1748-6041/5/6/065003. Epub 2010 Oct 6.
10
[Arthroscopy-guided core decompression and bone grafting combined with selective arterial infusion for treatment of early stage avascular necrosis of femoral head].关节镜引导下髓芯减压植骨联合选择性动脉灌注治疗早期股骨头缺血性坏死
Zhongguo Gu Shang. 2018 Jan 25;31(1):56-61. doi: 10.3969/j.issn.1003-0034.2018.01.010.

引用本文的文献

1
Injectable and Assembled Calcium Sulfate/Magnesium Silicate 3D Scaffold Promotes Bone Repair by In Situ Osteoinduction.可注射组装硫酸钙/硅酸镁3D支架通过原位骨诱导促进骨修复。
Bioengineering (Basel). 2025 May 31;12(6):599. doi: 10.3390/bioengineering12060599.
2
Effect of platelet-rich plasma combined with simvastatin in the treatment of steroid-induced avascular necrosis of the femoral head.富血小板血浆联合辛伐他汀治疗激素性股骨头缺血性坏死的疗效
Pak J Med Sci. 2025 May;41(5):1280-1284. doi: 10.12669/pjms.41.5.11518.
3
Variability in the classification, management, and outcome reporting for avascular necrosis of the femoral head: A systematic review.

本文引用的文献

1
The efficacy and safety of core decompression for the treatment of femoral head necrosis: a systematic review and meta-analysis.核心减压治疗股骨头坏死的疗效和安全性：系统评价和荟萃分析。
J Orthop Surg Res. 2019 Sep 11;14(1):306. doi: 10.1186/s13018-019-1359-7.
2
The role of autophagy in steroid necrosis of the femoral head: a comprehensive research review.自噬在股骨头类固醇性坏死中的作用：一项综合研究综述
Int Orthop. 2018 Jul;42(7):1747-1753. doi: 10.1007/s00264-018-3994-8. Epub 2018 May 25.
3
What is the rate of patients undergoing a total hip arthroplasty after core decompression and insertion of a tantalum rod in osteonecrosis of the femoral head: a systematic review.
股骨头缺血性坏死的分类、管理及结果报告的变异性：一项系统评价
J Orthop. 2025 Mar 26;63:148-156. doi: 10.1016/j.jor.2025.03.013. eCollection 2025 May.
4
Advancements in 3D printing technologies for personalized treatment of osteonecrosis of the femoral head.用于股骨头坏死个性化治疗的3D打印技术进展
Mater Today Bio. 2025 Feb 4;31:101531. doi: 10.1016/j.mtbio.2025.101531. eCollection 2025 Apr.
5
Core decompression assisted by multi-functional minimally invasive instruments for the treatment of early osteonecrosis of the femoral head.多功能微创器械辅助下的髓芯减压术治疗早期股骨头坏死
Sci Rep. 2025 Feb 19;15(1):6113. doi: 10.1038/s41598-025-90551-w.
6
Effectiveness of various interventions for non-traumatic osteonecrosis: a pairwise and network meta-analysis.各种干预措施治疗非创伤性骨坏死的有效性：成对和网络荟萃分析。
Front Endocrinol (Lausanne). 2024 Aug 21;15:1428125. doi: 10.3389/fendo.2024.1428125. eCollection 2024.
7
Subtrochanteric fracture after core decompression for osteonecrosis of the femoral head: a case report and literature review.股骨颈骨折核心减压术后：病例报告及文献复习。
BMC Musculoskelet Disord. 2024 May 29;25(1):420. doi: 10.1186/s12891-024-07536-5.
8
Impact of Femoral Neck Cortical Bone Defect Induced by Core Decompression on Postoperative Stability: A Finite Element Analysis.核心减压引起的股骨颈皮质骨缺损对术后稳定性的影响：有限元分析。
Biomed Res Int. 2022 May 20;2022:3667891. doi: 10.1155/2022/3667891. eCollection 2022.
9
Comparison of proximal femoral nail antirotation and total hip arthroplasty in the treatment of femoral intertrochanteric fracture.股骨近端防旋髓内钉与全髋关节置换术治疗股骨转子间骨折的比较
Pak J Med Sci. 2022 Mar-Apr;38(4Part-II):1016-1020. doi: 10.12669/pjms.38.4.5830.
10
Static Compressive Behavior and Material Failure Mechanism of Trabecular Tantalum Scaffolds Fabricated by Laser Powder Bed Fusion-based Additive Manufacturing.基于激光粉末床熔融增材制造的钽小梁支架的静态压缩行为及材料失效机制
Int J Bioprint. 2021 Oct 29;8(1):438. doi: 10.18063/ijb.v8i1.438. eCollection 2022.
在股骨头坏死患者中，进行髓芯减压和钽棒植入后接受全髋关节置换术的患者比例是多少：一项系统综述。
Int Orthop. 2018 Jul;42(7):1631-1638. doi: 10.1007/s00264-018-3961-4. Epub 2018 May 4.
4
Effectiveness of various hip preservation treatments for non-traumatic osteonecrosis of the femoral head: A network meta-analysis of randomized controlled trials.各种髋关节保留治疗对非创伤性股骨头坏死的有效性：一项随机对照试验的网状Meta分析
J Orthop Sci. 2018 Mar;23(2):356-364. doi: 10.1016/j.jos.2017.12.004. Epub 2017 Dec 29.
5
Modified porous tantalum rod technique for the treatment of femoral head osteonecrosis.改良多孔钽棒技术治疗股骨头坏死
World J Orthop. 2015 Nov 18;6(10):829-37. doi: 10.5312/wjo.v6.i10.829.
6
Stage-related results in treatment of hip osteonecrosis with core-decompression and autologous mesenchymal stem cells.采用髓芯减压术和自体间充质干细胞治疗股骨头坏死的分期相关结果。
Acta Orthop Belg. 2015 Sep;81(3):406-12.
7
Current concepts on osteonecrosis of the femoral head.当前关于股骨头坏死的概念
World J Orthop. 2015 Sep 18;6(8):590-601. doi: 10.5312/wjo.v6.i8.590.
8
Guideline for Diagnostic and Treatment of Osteonecrosis of the Femoral Head.股骨头坏死诊断与治疗指南
Orthop Surg. 2015 Aug;7(3):200-7. doi: 10.1111/os.12193.
9
Key pathway to prevent the collapse of femoral head in osteonecrosis.预防股骨头坏死中股骨头塌陷的关键途径。
Eur Rev Med Pharmacol Sci. 2015 Aug;19(15):2766-74.
10
Comparison of core decompression and conservative treatment for avascular necrosis of femoral head at early stage: a meta-analysis.早期股骨头缺血性坏死的核心减压术与保守治疗的比较：一项荟萃分析。
Int J Clin Exp Med. 2015 Apr 15;8(4):5207-16. eCollection 2015.