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通过考虑膳食暴露和风险评估来研究烤牛肉、鸡肉和鱼肉中多环芳烃(PAHs)的存在情况。

The Presence of Polycyclic Aromatic Hydrocarbons (PAHs) in Grilled Beef, Chicken and Fish by Considering Dietary Exposure and Risk Assessment.

作者信息

Sahin Seyda, Ulusoy Halil Ibrahim, Alemdar Suleyman, Erdogan Selim, Agaoglu Sema

机构信息

Department of Food Hygiene and Technology, Faculty of Veterinary Medicine, Sivas Cumhuriyet University, Sivas 58140, Turkey.

Department of Analytical Chemistry, Faculty of Pharmacy, Sivas Cumhuriyet University, Sivas 58140, Turkey.

出版信息

Food Sci Anim Resour. 2020 Sep;40(5):675-688. doi: 10.5851/kosfa.2020.e43. Epub 2020 Sep 1.

Abstract

Polycyclic aromatic hydrocarbons (PAHs) are dangerous chemical compounds that can be formed by cooking foods at high temperatures. The aim of this study is to determine the level of contamination of PAH compounds with high performance liquid chromatography (HPLC) on heat treated meat samples and the consumption of PAH compounds in meat samples, as well as the dietary exposure status and possible health risk estimation. In five different heat treated meat samples (meat doner, chicken doner, meatballs, grilled chicken, and fish), the total PAH (Σ16PAH) contamination level was 6.08, 4.42, 4.45, 4.91, and 7.26 μg/kg, respectively. Benzo[a]pyrene (BaP) in meatballs and grilled fish samples had a level 0.70 and 0.73 μg/kg. All of the samples analyzed were found to be below the EU permitted limit (5 μg/kg) in terms of BaP. Estimates of daily intake (EDI) for a total of 16PAH in heat treated meat doner, chicken doner, meatballs, grilled chicken and fish samples were 3.41, 3.71, 2.49, 4.12, and 1.77 ng/kg bw/day, respectively. In this study, the average margin of exposure (MOE) value calculated was found in the range of 179.487 and 425.000 for BaP and PAH4. This study is the first study to provide important information in terms of evaluating the possible health risk that PAH compounds can create in people's diets due to heat treatment of meat and meat products in Sivas, Turkey.

摘要

多环芳烃(PAHs)是危险的化合物,可通过高温烹饪食物形成。本研究的目的是用高效液相色谱法(HPLC)测定热处理肉类样品中PAH化合物的污染水平、肉类样品中PAH化合物的摄入量,以及膳食暴露状况和可能的健康风险评估。在五个不同的热处理肉类样品(烤肉串、鸡肉烤肉串、肉丸、烤鸡和鱼)中,总PAH(Σ16PAH)污染水平分别为6.08、4.42、4.45、4.91和7.26μg/kg。肉丸和烤鱼样品中的苯并[a]芘(BaP)含量分别为0.70和0.73μg/kg。就BaP而言,所有分析的样品均低于欧盟允许限量(5μg/kg)。热处理的烤肉串、鸡肉烤肉串、肉丸、烤鸡和鱼样品中总共16种PAH的每日摄入量(EDI)估计分别为3.41、3.71、2.49、4.12和1.77 ng/kg体重/天。在本研究中,计算得出的BaP和PAH4的平均暴露边际(MOE)值在179.487至425.000范围内。本研究是第一项在评估土耳其锡瓦斯因肉类和肉制品热处理而导致PAH化合物在人们饮食中可能产生的健康风险方面提供重要信息的研究。

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