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食物成瘾与精神共病:当前证据综述。

Food addiction and psychiatric comorbidities: a review of current evidence.

机构信息

Unicamillus, Saint Camillus International University of Health Sciences, Rome, Italy.

Brain Research Foundation (BRF), Via Berlinghieri 15, 55100, Lucca, Italy.

出版信息

Eat Weight Disord. 2021 May;26(4):1049-1056. doi: 10.1007/s40519-020-01021-3. Epub 2020 Sep 23.

DOI:10.1007/s40519-020-01021-3
PMID:32968944
Abstract

BACKGROUND

Food addiction (FA) is characterised by the consumption of appetible foods and by addictive psychological and behavioural symptoms such as cravings, tolerance, limited control of substance intake and withdrawal symptoms. Despite previous research on FA has been hindered by the lack of a formal definition for this condition, recent global trends have stirred the interest of the scientific community towards a proper classification and construct of FA. More specifically, recent studies have pointed towards shared defective neurobiological mechanisms as well as frequent comorbidities between FA, eating disorders, mood disorders, anxiety disorders and substance-related and addictive disorders.

OBJECTIVE

In this review, we will provide an overview of the complex symptomatology of food addiction evaluating its relationship with mood disorders, anxiety disorders, eating disorders and substance-related and addictive disorders.

METHODS

We wrote a systematic review and followed a PRISMA methods.

RESULTS

Patients with FA and substance use disorders show similar risk factors, neurobiological and hormonal correlates, personality traits and symptom profiles. The presence of FA appears to be directly proportional to the burden of symptoms of affective disorder. The comorbidity between FA and other eating disorders is associated with worse clinical conditions and symptoms.

CONCLUSION

FA should be considered a sort of transnosological construct existing in different psychopathological domains that have similarities with substance-related, affective, and eating disorders. Furthermore, FA seems to be likely an important factor related to several psychopathological dimensions, but further studies are needed to clarify this view.

LEVEL OF EVIDENCE

Level V, review article.

摘要

背景

食物成瘾(FA)的特征是食用有吸引力的食物以及成瘾的心理和行为症状,如渴望、耐受、对物质摄入的有限控制和戒断症状。尽管之前对 FA 的研究受到该病症缺乏正式定义的阻碍,但最近全球趋势引起了科学界对 FA 的适当分类和构建的兴趣。更具体地说,最近的研究指出,FA 与饮食失调、情绪障碍、焦虑障碍以及物质相关和成瘾障碍之间存在共同的神经生物学缺陷机制和频繁的共病。

目的

在这篇综述中,我们将概述食物成瘾的复杂症状学,评估其与情绪障碍、焦虑障碍、饮食失调和物质相关及成瘾障碍的关系。

方法

我们撰写了一篇系统综述,并遵循了 PRISMA 方法。

结果

患有 FA 和物质使用障碍的患者表现出相似的风险因素、神经生物学和激素相关性、人格特质和症状特征。FA 的存在似乎与情感障碍症状的负担成正比。FA 与其他饮食失调的共病与更差的临床状况和症状相关。

结论

FA 应被视为存在于不同精神病理学领域的一种跨疾病学结构,与物质相关、情感和饮食障碍具有相似性。此外,FA 似乎很可能是与几个精神病理学维度相关的重要因素,但需要进一步研究来澄清这一观点。

证据水平

五级,综述文章。

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