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拓展审计对在全科医疗中识别心力衰竭患者的影响:OSCAR-HF 试点研究的基线结果

Impact of an extended audit on identifying heart failure patients in general practice: baseline results of the OSCAR-HF pilot study.

作者信息

Smeets Miek, Vaes Bert, Aertgeerts Bert, Raat Willem, Penders Joris, Vercammen Jan, Droogne Walter, Mullens Wilfried, Janssens Stefan

机构信息

Department of Public Health and Primary Care, KU Leuven (KUL), Leuven, Belgium.

Institute of Health and Society, Université Catholique de Louvain (UCL), Brussels, Belgium.

出版信息

ESC Heart Fail. 2020 Dec;7(6):3950-3961. doi: 10.1002/ehf2.12990. Epub 2020 Sep 24.

Abstract

AIMS

Identifying heart failure (HF) patients in general practice is challenging, and little is known about the current quality of care. We implemented an extended audit from the electronic health records (EHRs) of general practitioners (GPs) to identify HF patients and investigate patient characteristics and quality of care.

METHODS AND RESULTS

This study describes the baseline results of the OSCAR-HF pilot study in eight general practices (51 GPs) in Flanders, Belgium. This prospective trial ran for 6 months. Interventions included an extended audit, an N-terminal pro-B-type natriuretic peptide point-of-care test, and assistance of a specialist HF nurse. The extended audit searched on risk factors for HF, HF symptoms, signs, and medication in the GPs' EHR to generate a list of possible HF patients. GPs determined which patients had HF. Those HF patients constituted the OSCAR-HF study population. Each patient file was manually revised to extract biomarker measurements, echocardiography data, and quality indicators. An independent panel of experts assessed the validity of GPs' HF diagnoses. Feedback about the validity of the HF diagnosis was given to the GP. Out of 18 011 patients ≥ 40 years, we identified 310 patients with a registered HF diagnosis before the study start (HF prevalence: 1.7%). The extended audit led to a 74% increase in identified HF patients (n = 538, HF prevalence: 3.0%) with a mean age of 79 ± 11 years. The prevalence of HF with reduced ejection fraction (HFrEF) was 20% (n = 110). A high proportion of patients underwent echocardiography in the past 5 years (86%, n = 462). Natriuretic peptides were rarely available in patients' files (19%, n = 100). Medical specialists should improve communication about the HF diagnosis because a specialist diagnosis was present in only 225 patients (42%) while 67% (n = 359) of the HF diagnoses were judged objectified by a panel of experts. Assigning a diagnosis of HF was particularly difficult in HF patients with preserved EF (HFpEF). HFrEF treatment rates with renin-angiotensin-aldosterone system blockers (84%, n = 92) and beta-blockers (86%, n = 94) were very good; however, target doses were hardly reached (34% and 14%, respectively).

CONCLUSIONS

This study highlighted the need to improve case finding for HF in general practice and showed that an extended audit in the GPs' EHR was a successful strategy to do so. To improve the quality of HF care in general practice, specific strategies are needed to diagnose HFpEF and to reach target doses of disease-modifying drugs in HFrEF patients.

摘要

目的

在全科医疗中识别心力衰竭(HF)患者具有挑战性,目前对医疗质量了解甚少。我们通过全科医生(GP)的电子健康记录(EHR)进行了一项扩展审计,以识别HF患者并调查患者特征和医疗质量。

方法与结果

本研究描述了比利时弗拉芒地区8家全科诊所(51名GP)中OSCAR - HF试点研究的基线结果。这项前瞻性试验持续了6个月。干预措施包括扩展审计、N末端B型利钠肽原即时检测以及一名HF专科护士的协助。扩展审计在GP的EHR中搜索HF的危险因素、HF症状、体征和用药情况,以生成可能的HF患者名单。GP确定哪些患者患有HF。这些HF患者构成了OSCAR - HF研究人群。每个患者档案都经过人工修订,以提取生物标志物测量值、超声心动图数据和质量指标。一个独立的专家小组评估了GP对HF诊断的有效性。向GP提供了关于HF诊断有效性的反馈。在18011名年龄≥40岁的患者中,我们在研究开始前确定了310名有HF诊断记录的患者(HF患病率:1.7%)。扩展审计使识别出的HF患者增加了74%(n = 538,HF患病率:3.0%),平均年龄为79±11岁。射血分数降低的HF(HFrEF)患病率为20%(n = 110)。过去5年中,很大一部分患者接受了超声心动图检查(86%,n = 462)。患者档案中利钠肽很少可得(19%,n = 100)。医学专家应改善关于HF诊断的沟通,因为只有225名患者(42%)有专科诊断,而专家小组判断67%(n = 359)的HF诊断是客观的。在射血分数保留的HF(HFpEF)患者中,做出HF诊断尤其困难。HFrEF患者使用肾素 - 血管紧张素 - 醛固酮系统阻滞剂(84%,n = 92)和β受体阻滞剂(86%,n = 94)的治疗率非常高;然而,很少达到目标剂量(分别为34%和14%)。

结论

本研究强调了在全科医疗中改善HF病例发现的必要性,并表明在GP的EHR中进行扩展审计是实现这一目标的成功策略。为了提高全科医疗中HF的护理质量,需要采取特定策略来诊断HFpEF,并使HFrEF患者达到疾病修饰药物的目标剂量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ac2/7754725/84465557ae05/EHF2-7-3950-g001.jpg

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