First Department of Surgery, Laiko General Hospital, National and Kapodistrian University of Athens, Greece.
First Department of Pathology, Laiko General Hospital, National and Kapodistrian University of Athens, Greece.
Ann R Coll Surg Engl. 2021 Jan;103(1):e13-e16. doi: 10.1308/rcsann.2020.0193. Epub 2020 Sep 24.
Renal cell carcinoma (RCC) accounts for approximately 3% of all adult malignancies. A third of people with RCC have metastatic lesions when diagnosed, and another third develop metachronous metastasis during follow-up or after surgical treatment. We report a case of gallbladder metastasis from clear-cell RCC in a 71-year-old woman 13 years after RCC of her right kidney. Preoperative imaging studies showed a suspicious, progressively enlarged gallbladder polyp. The patient underwent open cholecystectomy and lymph node dissection along the hepatoduodenal ligament. The pathology report was compatible with metastatic disease from the kidney that was previously resected. Gallbladder metastasis can occur from RCC several years after initial management. Physicians should be aware of this rare pathology, and intensive follow-up is essential after surgery for RCC.
肾细胞癌（RCC）约占所有成人恶性肿瘤的 3%。三分之一的 RCC 患者在诊断时已有转移病灶，另有三分之一在随访或肾切除术后发生异时性转移。我们报告了一例右肾癌 13 年后发生于胆囊的透明细胞 RCC 转移。术前影像学检查显示可疑的、逐渐增大的胆囊息肉。患者接受了开放性胆囊切除术和肝十二指肠韧带淋巴结清扫术。病理报告与之前切除的肾脏转移疾病相符。RCC 初始治疗后数年可能发生胆囊转移。医生应了解这种罕见的病理情况，RCC 手术后进行强化随访至关重要。
