肺部外结核患者的 68Ga-FAPI 和 18F-FDG PET/CT 图像，其表现类似恶性肿瘤。

From the Department of Nuclear Medicine, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, and Center for Biomedical Imaging, Fudan University; Shanghai Engineering Research Center of Molecular Imaging Probes.

Departments of Medical Oncology.

Clin Nucl Med. 2020 Nov;45(11):865-867. doi: 10.1097/RLU.0000000000003279.

Extrapulmonary tuberculosis (TB) is difficult to diagnose. Here, we report a case of extrapulmonary TB in a 68-year-old woman presented with mental fatigue, poor appetite, and weight loss. F-FDG PET/CT revealed elevated F-FDG uptake in the left inferior cervical, left supraclavicular, mediastinal, and splenic hilum lymph nodes and spleen, which were suspected of malignant tumor. To further differentiate benign and malignant diseases, Ga-FAPI PET/CT was performed. Ga-FAPI PET/CT also showed intense Ga-FAPI uptake in the previously mentioned FDG-avid lesions. However, biopsy of the left supraclavicular lymph node demonstrated the presence of TB.

肺外结核（TB）的诊断较为困难。本文报道了 1 例以精神疲劳、食欲不振和体重减轻为表现的 68 岁女性肺外 TB 病例。18F-FDG PET/CT 显示左颈下部、左锁骨上、纵隔和脾门淋巴结及脾脏摄取 18F-FDG 增高，考虑恶性肿瘤。为进一步鉴别良恶性疾病，行 Ga-FAPI PET/CT 检查。Ga-FAPI PET/CT 也显示上述 FDG 摄取增高的病灶摄取 Ga-FAPI 增加。然而，左锁骨上淋巴结活检显示存在结核。