Department of Rheumatology, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, People's Republic of China.
Clin Nucl Med. 2020 Apr;45(4):310-311. doi: 10.1097/RLU.0000000000002914.
Contrast CT revealed diffuse enlargement of the pancreas with a suspicious lesion in the uncinate process in a 57-year-old man who presented with jaundice. F-FDG PET/CT showed increased radioactivity in the enlarged pancreas with a nodular lesion with even higher uptake in the uncinate process. To differentiate autoimmune pancreatitis and pancreatic cancer, Ga-FAPI PET/CT was performed. It revealed intense Ga-FAPI uptake in the pancreas, but the FDG-avid lesion in the uncinate process was not shown. The patient was finally diagnosed with pancreatic cancer with tumor-induced pancreatitis with endoscopic ultrasonography-guided biopsy.
对比 CT 显示，一位 57 岁的男性患者出现黄疸，胰腺弥漫性肿大，钩突处有可疑病变。18F-FDG PET/CT 显示肿大的胰腺放射性摄取增加，呈结节状病变，在钩突处摄取更高。为了区分自身免疫性胰腺炎和胰腺癌，进行了 Ga-FAPI PET/CT 检查。结果显示胰腺摄取 Ga-FAPI 明显增加，但在钩突处未见 FDG 摄取的病变。最终，患者通过内镜超声引导活检被诊断为胰腺癌伴肿瘤诱导性胰腺炎。
