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[与急性呼吸道感染相关的细菌性和真菌性病因肠道病变的形态学表现]

[Morphologic manifestations of intestinal lesions of bacterial and mycotic etiology developing in association with acute respiratory infections].

作者信息

Shastina G V

出版信息

Arkh Patol. 1987;49(3):37-44.

PMID:3297004
Abstract

By means of light and immunofluorescent microscopy the intestines of 34 children were studied, whose bacterial or mycotic enterocolitis most often combined with acute respiratory infections. Intestinal lesions were caused either by virus (sometimes by Mycoplasma), or by bacteria and fungi. Such changes developed in the debilitated children and their course was more severe, than in monoinfections because of the impaired systemic and local immunity, and probably due to formation of viral-bacterial complexes. Viral intestinal lesions were most often caused by a single virus, but not by multiple ones, as in pulmonary infections, which is explained by interferon production and the intensive therapy used. The alternative component in a viral lesion is enhanced due to the presence of lactic acid in the intestine and therefore it is inhibited when acute viral respiratory infection develops against the background of bacterial or mycotic enterocolitis due to dysbacteriosis. Changes in mucosal stroma and intestinal lymphatic system in different infections depend on the duration of the intestinal lesion.

摘要

通过光学显微镜和免疫荧光显微镜对34名儿童的肠道进行了研究,这些儿童的细菌性或霉菌性小肠结肠炎最常与急性呼吸道感染合并发生。肠道病变是由病毒(有时是支原体)、细菌或真菌引起的。这种变化发生在体弱的儿童中,由于全身和局部免疫力受损,其病程比单一感染更为严重,可能还由于病毒-细菌复合物的形成。病毒性肠道病变最常由单一病毒引起,而不像肺部感染那样由多种病毒引起,这是由干扰素的产生和所采用的强化治疗所解释的。由于肠道中存在乳酸,病毒性病变中的替代成分会增强,因此当急性病毒性呼吸道感染在细菌性或霉菌性小肠结肠炎背景下因菌群失调而发生时,它会受到抑制。不同感染中黏膜基质和肠道淋巴系统的变化取决于肠道病变的持续时间。

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