Kan'shina N F, Evdokimov E V
Arkh Patol. 1983;45(7):20-5.
Morphological lesions of the kidneys in 59 autopsy observations of acute intestinal infections in children were studied. The greatest disorders were found in patients with the toxico-septic form of intestinal infections complicated by the development of bacterial shock. Impairments of the microcirculatory hemodynamics accompanied by dystrophic and necrotic changes in the epithelium of the tubules underlie renal lesions. These changes directly depend on the duration of bacterial shock. With a protracted course of bacterial shock acute renal insufficiency develops. In other forms of the disease renal lesions are insignificant and do not constitute a serious part of tanatogenesis.
对59例儿童急性肠道感染尸检病例的肾脏形态学病变进行了研究。在伴有细菌性休克的中毒性败血症型肠道感染患者中发现了最严重的病变。微循环血液动力学障碍伴有肾小管上皮的营养不良和坏死性变化是肾脏病变的基础。这些变化直接取决于细菌性休克的持续时间。随着细菌性休克病程的延长,急性肾功能不全逐渐发展。在疾病的其他形式中,肾脏病变不明显,并非死因的重要组成部分。