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增殖性糖尿病性视网膜病变导致视网膜脱离行玻璃体切除术后达到视敏度的功能水平。

Attaining functional levels of visual acuity after vitrectomy for retinal detachment secondary to proliferative diabetic retinopathy.

机构信息

Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA, 52242, USA.

Carver College of Medicine, University of Iowa, Iowa City, IA, USA.

出版信息

Sci Rep. 2020 Sep 24;10(1):15637. doi: 10.1038/s41598-020-72618-y.

Abstract

Most patients needing diabetic tractional retinal detachment (TRD) surgery are working-age adults that drive and participate in other vision-dependent activities of daily living. We sought to determine the proportion of patients that achieve functional visual acuity (VA) based on the World Health Organization (WHO) definition of 'low vision' (≤ 20/80) and US driving standards (≥ 20/40) after vitrectomy for diabetic TRD. In this 10-year retrospective review, consecutive patients who underwent primary vitrectomy for TRD from proliferative diabetic retinopathy were studied. 240 eyes in 203 patients met criteria for analysis (38 eyes were lost to follow up at 3 months; 68 at 12 months; 146 at 60 months). While most patients (nearly 80%) having TRD surgery had low vision pre-op, almost half attained VA that was > 20/80 five years post-op. Those most likely to achieve significant visual improvement (p < 0.0001) had concomitant vitreous hemorrhage pre-op. Only 6% of eyes met the US minimum driving standard before surgery based on VA compared to 28% after vitrectomy however this study did not examine visual fields which could warrant additional assessment depending on local requirements. In summary, significant gains in visual acuity are seen after vitrectomy for diabetic TRD that can result in functional improvement in activities of daily living.

摘要

大多数需要糖尿病牵引性视网膜脱离(TRD)手术的患者是工作年龄段的成年人,他们需要驾驶并参与其他依赖视力的日常生活活动。我们旨在确定接受玻璃体切割术治疗糖尿病性 TRD 后,根据世界卫生组织(WHO)对“低视力”(≤20/80)和美国驾驶标准(≥20/40)的定义,患者实现功能性视力(VA)的比例。在这项为期 10 年的回顾性研究中,对患有增殖性糖尿病性视网膜病变的患者进行了原发性玻璃体切除术治疗 TRD 的连续患者进行了研究。203 名患者的 240 只眼符合分析标准(3 个月时失访 38 只眼;12 个月时失访 68 只眼;60 个月时失访 146 只眼)。虽然大多数接受 TRD 手术的患者(近 80%)术前视力较差,但近一半的患者在术后 5 年达到了 >20/80 的 VA。术前伴有玻璃体积血的患者最有可能获得显著的视力改善(p<0.0001)。然而,与术前相比,只有 6%的眼睛在手术后根据 VA 符合美国最低驾驶标准,而术后则为 28%,但本研究并未检查视野,根据当地要求,可能需要进行额外评估。总之,糖尿病性 TRD 接受玻璃体切割术后视力显著提高,可以改善日常生活活动的功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1830/7519031/82f4f9b2c154/41598_2020_72618_Fig1_HTML.jpg

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