Author Affiliations: Department of Basic Nursing, Medical School of Nantong University (Mss Xie and Shi), and Department of Nursing, Hospital Affiliated to Nantong University (Ms Shen); and Department of Humanistic Care, Nursing School of Medical College, Soochow University, Suzhou (Dr Li), China.
Cancer Nurs. 2021;44(6):E556-E566. doi: 10.1097/NCC.0000000000000895.
Patients undergoing hematopoietic stem cell transplantation (HSCT) require extensive care, and their caregivers were previously found to experience high levels of caregiver's burden. However, the current status of HSCT patient caregiver burden in Suzhou, China, is still unknown.
To investigate the current status of caregiver burden among family caregivers of HSCT patients from Suzhou, China, and explore the related factors of caregiver burden.
This cross-sectional study enrolled 116 HSCT patient-caregiver dyads. The following measurement tools were used: a demographic questionnaire, Zarit Burden Interview, and World Health Organization Quality of Life questionnaire (brief version). Multiple regression model was used to analyze the factors associated with caregiver burden, and the relationship between caregiver burden and quality of life was analyzed.
Caregivers' marital status, family monthly income, duration of caregiving, daily caregiving time, other cocaregivers, transplant-related complications, and relapse were closely related to caregiver burden, and 75.4% of the variance in caregivers' burden was explained by these factors. A negative correlation between caregiver burden and quality of life was noted.
The HSCT patient caregivers' burden noted in this study was higher than that found in previous studies. The quality of life of HSCT patient caregivers is lower than that of the average Chinese population and decreases with a greater sense of burden.
Hematopoietic stem cell transplantation patient caregivers should be given appropriate social support to reduce their burden of care. Factors identified in this study may help center future intervention programs on caregivers who need help the most.
接受造血干细胞移植（HSCT）的患者需要广泛的护理，先前研究发现其照顾者的负担水平较高。然而，目前中国苏州 HSCT 患者照顾者负担的现状仍不清楚。
调查中国苏州 HSCT 患者家庭照顾者目前的负担状况，并探讨照顾者负担的相关因素。
本横断面研究纳入了 116 对 HSCT 患者-照顾者。使用以下测量工具：人口统计学问卷、Zarit 负担量表和世界卫生组织生活质量量表（简表）。采用多元回归模型分析与照顾者负担相关的因素，并分析照顾者负担与生活质量之间的关系。
照顾者的婚姻状况、家庭月收入、照顾时间、每日照顾时间、其他共同照顾者、移植相关并发症和复发与照顾者负担密切相关，这些因素解释了照顾者负担 75.4%的方差。照顾者负担与生活质量呈负相关。
本研究中 HSCT 患者照顾者的负担高于以往研究。HSCT 患者照顾者的生活质量低于中国普通人群，且随着负担感的增加而降低。
应给予造血干细胞移植患者照顾者适当的社会支持，以减轻其照顾负担。本研究确定的因素可能有助于以最需要帮助的照顾者为中心，开展未来的干预项目。
