Son Elisa H, Lee Lena J, Yang Li, Gerrard Chantal, Wallen Gwenyth R
National Institutes of Health, Clinical Center, Bethesda, USA.
National Institutes of Health, Clinical Center, Bethesda, USA.
Complement Ther Med. 2025 Oct;93:103212. doi: 10.1016/j.ctim.2025.103212. Epub 2025 Jul 21.
This study used a concurrent triangulation mixed-methods design to assess the acceptability of a yoga-based stress reduction intervention in family caregivers of hematopoietic stem cell transplant (HSCT) recipients.
This study was a part of a randomized controlled trial. Of the 50 caregivers recruited, we analyzed data from 25 caregivers assigned to the intervention group. Participants were asked to practice the intervention 20 min per day for six weeks and record it in a practice diary. Surveys were administered at baseline and Week 6, and interviews were conducted at Week 2, Week 4, and Week 6. Non-parametric statistics on quantitative data and thematic analysis on qualitative data were compared in parallel. As part of triangulation, we examined the association between thematic analysis and total minutes of the intervention practice.
Thematic analysis revealed the challenges and benefits participants experienced while practicing the intervention, with caregiver burden as a main barrier to practice. The number of participants perceiving that the intervention helps them relax and sleep increased over time. The quantitative analysis validated the benefits of practicing the intervention with the measures of sleep disturbance and health behaviors. Perceptions of caregiver burden and benefits of the intervention identified in thematic analysis were associated with total practice minutes. Researchers and clinicians may refer to the current findings when developing stress reduction intervention programs tailored for HSCT caregivers. Changes in caregiver burden along the HSCT trajectory should be considered when implementing such programs.
本研究采用并行三角互证混合方法设计，以评估基于瑜伽的减压干预措施在造血干细胞移植（HSCT）受者家庭照顾者中的可接受性。
本研究是一项随机对照试验的一部分。在招募的50名照顾者中，我们分析了分配到干预组的25名照顾者的数据。参与者被要求每天进行20分钟的干预练习，持续六周，并记录在练习日记中。在基线和第6周进行调查，并在第2周、第4周和第6周进行访谈。对定量数据进行非参数统计，同时对定性数据进行主题分析。作为三角互证的一部分，我们研究了主题分析与干预练习总时长之间的关联。
主题分析揭示了参与者在进行干预练习时所经历的挑战和益处，照顾者负担是练习的主要障碍。随着时间的推移，认为干预有助于他们放松和睡眠的参与者人数有所增加。定量分析通过睡眠障碍和健康行为指标验证了进行干预的益处。主题分析中确定的照顾者负担认知和干预益处与总练习时长相关。研究人员和临床医生在为HSCT照顾者制定减压干预计划时可参考当前研究结果。实施此类计划时应考虑HSCT过程中照顾者负担的变化。
