富血小板血浆在慢性乳腺伤口治疗中的新应用：一项前瞻性观察研究。
A New Therapeutic Application of Platelet-Rich Plasma to Chronic Breast Wounds: A Prospective Observational Study.
作者信息
Berná-Serna Juan de Dios, Guzmán-Aroca Florentina, García-Vidal José A, Hernández-Gómez Dolores, García-Ortega Ana Azahara, Chivato Martín-Falquina Tomás, Piñero-Madrona Antonio, Berná-Mestre Juan de Dios
机构信息
Department of Radiology, Hospital Clínico Universitario "Virgen de la Arrixaca", Ctra. Madrid-Cartagena, 30120 El Palmar (Murcia), Spain.
Instituto Murciano de Investigación Biosanitaria "Virgen de la Arrixaca" (IMIB-Arrixaca), 30100 Murcia, Spain.
出版信息
J Clin Med. 2020 Sep 23;9(10):3063. doi: 10.3390/jcm9103063.
The aim of this study was to investigate the usefulness of platelet-rich plasma (PRP) treatment for chronic wounds (CWs) of the breast. A prospective study was performed in 23 patients with CW of the breast who were treated with PRP. The procedure was repeated until the wound was closed completely. The study included patients with a history of breast cancer ( = 8) and patients without cancer ( = 15). The treatment with PRP was successful in all cases and observed in ≤4 weeks in 82.6% (19/23) of patients. The patients without breast cancer showed significantly less time for wound closure than the patients with a history of breast cancer. Moreover, a greater number of PRP treatments were necessary to achieve wound closure in patients undergoing conservative breast treatment. No patients had complications associated with the application of PRP. Conclusions: To the best of our knowledge, this is the first study to reveal that PRP treatment for CWs of the breast is safe, simple, useful and well-tolerated by patients.
本研究的目的是探讨富血小板血浆（PRP）治疗乳腺慢性伤口（CWs）的有效性。对23例接受PRP治疗的乳腺CW患者进行了一项前瞻性研究。该操作重复进行，直到伤口完全愈合。该研究纳入了有乳腺癌病史的患者（n = 8）和无癌症的患者（n = 15）。PRP治疗在所有病例中均获成功，82.6%（19/23）的患者在≤4周内观察到伤口愈合。无乳腺癌的患者伤口愈合时间明显短于有乳腺癌病史的患者。此外，接受保守乳腺治疗的患者需要更多次数的PRP治疗才能实现伤口愈合。没有患者出现与PRP应用相关的并发症。结论：据我们所知，这是第一项揭示PRP治疗乳腺CWs安全、简单、有效且患者耐受性良好的研究。
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