Fan Yijiao, Perez Karla, Dym Harry
Division of Oral and Maxillofacial Surgery, The Brooklyn Hospital Center, 121 DeKalb Avenue, Brooklyn, NY 11201, USA.
Department of Dentistry and Oral & Maxillofacial Surgery, The Brooklyn Hospital Center, Outpatient Care Building-1st Floor, 121 DeKalb Avenue, Brooklyn, NY 11201, USA.
Dent Clin North Am. 2020 Apr;64(2):291-303. doi: 10.1016/j.cden.2019.12.012. Epub 2020 Feb 3.
Platelet-rich fibrin (PRF) is an autogenous material that is derived from a person's own platelets and is used to enhance wound healing and tissue regeneration. Platelet concentrates have been applied in dermatology, pain management, sports medicine, plastic surgery, cardiac surgery, urology, and also dentistry. PRF has garnered significant interest in the dental community because of its proposed regenerative properties and its ability to aid in wound healing. PRF is proposed to have a direct effect on enhancing a patient's wound healing by suprasaturating the wound with growth factors that promote tissue healing. Clinically, PRF is easily produced chairside from the patient's own blood. The autologous nature of PRF makes it preferred over a variety of allografts used in dentistry today. Therefore, PRF has significant potential in being applicable to all areas of dentistry, including oral and maxillofacial surgeries.
富血小板纤维蛋白（PRF）是一种自体材料，它源自人体自身的血小板，用于促进伤口愈合和组织再生。血小板浓缩物已应用于皮肤科、疼痛管理、运动医学、整形手术、心脏手术、泌尿外科以及牙科。由于其潜在的再生特性和促进伤口愈合的能力，PRF在牙科领域引起了极大的关注。PRF被认为可通过用促进组织愈合的生长因子使伤口超饱和，从而对增强患者的伤口愈合产生直接影响。临床上，PRF可在椅旁轻松地从患者自身血液中制备。PRF的自体性质使其比当今牙科中使用的各种同种异体移植物更受青睐。因此，PRF在适用于牙科的所有领域（包括口腔颌面外科手术）方面具有巨大潜力。
