[乳腺癌风险评估与管理咨询的初步结果]
[First results of a breast cancer risk assessment and management consultation].
作者信息
Uzan Catherine, Ndiaye-Guèye Diaretou, Nikpayam Marianne, Oueld Es Cheikh Eva, Lebègue Geraldine, Canlorbe Geoffroy, Azais Henri, Gonthier Clementine, Belghiti Jeremie, Benusiglio Patrick R, Séroussi Brigitte, Gligorov Joseph, Uzan Serge
机构信息
AP-HP, hôpital Pitié-Salpêtrière, Sorbonne Université, service de chirurgie et cancérologie gynécologique et mammaire, 47-83, boulevard de l'Hôpital, 75013 Paris, France; Inserm UMR S938 « Biologie et thérapeutique des cancers », Paris, France; AP-HP, institut universitaire de cancérologie, Sorbonne Université (IUC AP-HP.SU), Paris, France.
AP-HP, institut universitaire de cancérologie, Sorbonne Université (IUC AP-HP.SU), Paris, France.
出版信息
Bull Cancer. 2020 Oct;107(10):972-981. doi: 10.1016/j.bulcan.2020.08.003. Epub 2020 Sep 23.
INTRODUCTION
In France, participation in the organized breast cancer screening program remains insufficient. A personalized approach adapted to the risk factors for breast cancer (RBC) should make screening more efficient. A RBC evaluation consultation would therefore make it possible to personalize this screening. Here we report our initial experience.
MATERIAL AND METHOD
This is a prospective study on women who were seen at the RBC evaluation consultation and analyzing: their profile, their risk assessed according to Tyrer Cuzick model (TC)±Mammorisk© (MMR), the existence of an indication of oncogenetic consultation (Eisinger and Manchester score), their satisfaction and the recommended monitoring.
RESULTS
Among the women who had had a TCS and/or MMR evaluation of SCR (n=153), 76 (50%) had a high risk (n=67) or a very high risk (n=9). Almost half (47%) had a possible (15%) or certain (32%) indication to an oncogenetic consultation. Regarding this consultation, 98% of women were satisfied or very satisfied. In total, 60% of women had a change in screening methods.
CONCLUSION
This RBC evaluation consultation satisfies women and for a majority of them, modifies their methods of breast cancer screening.
引言
在法国，参与有组织的乳腺癌筛查项目的情况仍然不理想。采用适应乳腺癌风险因素的个性化方法应能提高筛查效率。因此，进行乳腺癌风险评估咨询将使这种筛查能够实现个性化。在此，我们报告我们的初步经验。
材料与方法
这是一项针对在乳腺癌风险评估咨询中接受检查的女性的前瞻性研究，分析她们的特征、根据泰勒·库齐克模型（TC）±乳腺风险评估（MMR）评估的风险、存在遗传咨询指征（艾辛格和曼彻斯特评分）、她们的满意度以及推荐的监测措施。
结果
在对153名女性进行了TC和/或MMR的SCR评估中，76名（50%）有高风险（67名）或极高风险（9名）。几乎一半（47%）有进行遗传咨询的可能指征（15%）或确定指征（32%）。关于这种咨询，98%的女性表示满意或非常满意。总体而言，60%的女性的筛查方法有改变。
结论
这种乳腺癌风险评估咨询让女性满意，并且对大多数女性而言，改变了她们的乳腺癌筛查方法。
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