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髋关节置换术后色素绒毛结节性滑膜炎:一项回顾性病例对照分析。

Pigmented Villonodular Synovitis of the Hip in Patients Undergoing Total Hip Arthroplasty: A Retrospective Case-Controlled Analysis.

机构信息

Nova Southeastern College of Osteopathic Medicine, Fort Lauderdale, FL; Department of Orthopaedic Research, Orthopaedic Research Institute, Fort Lauderdale, FL.

Department of Orthopaedic Research, Orthopaedic Research Institute, Fort Lauderdale, FL; Harvard Medical School, Harvard University, Boston, MA.

出版信息

J Arthroplasty. 2021 Mar;36(3):1018-1022. doi: 10.1016/j.arth.2020.08.064. Epub 2020 Sep 7.

Abstract

BACKGROUND

Pigmented villonodular synovitis (PVNS) is a condition affecting larger joints such as the hip and knee. Little is known regarding the impact of PVNS on total hip arthroplasty (THA). Therefore, the aim of this study is to determine if patients with PVNS of the hip undergoing primary THA experience greater (1) in-hospital lengths of stay (LOS); (2) complications; (3) readmission rates; and (4) costs.

METHODS

Patients undergoing primary THA for PVNS of the hip from the years 2005 to 2014 were identified using a nationwide claims registry. PVNS patients were matched to a control cohort in a 1:5 ratio by age, gender, and various comorbidities. The query yielded 7440 patients with (n = 1240) and without (n = 6200) PVNS of the hip undergoing primary THA. Endpoints analyzed included LOS, complications, readmission rates, and costs. Multivariate logistic regression was used to determine odds ratios (OR) of developing complications. Welch's t-tests were used to test for significance in LOS and cost between the cohorts. A P-value less than .001 was considered statistically significant.

RESULTS

PVNS patients had approximately 8% longer in-hospital LOS (3.8 vs 3.5 days, P = .0006). PVNS patients had greater odds of (OR 1.60, P < .0001) medical and (OR 1.81, P < .0001) implant-related complications. Furthermore, PVNS patients were found to have higher odds (OR 1.84, P < .0001) of 90-day readmissions. PVNS patients also incurred higher day of surgery ($13,119 vs $11,983, P < .0001) and 90-day costs ($17,169 vs $15,097, P < .0001).

CONCLUSION

Without controlling for global trends in LOS, complications, readmissions, or costs between 2005 and 2014, the findings of the study suggest that PVNS of the hip is associated with worse outcomes and higher costs following primary THA. The study is useful as orthopedic surgeons can use the study to educate patients of the complications which may occur following their hip surgery.

摘要

背景

色素绒毛结节性滑膜炎(PVNS)是一种影响髋关节和膝关节等大关节的疾病。目前对于 PVNS 对全髋关节置换术(THA)的影响知之甚少。因此,本研究旨在确定髋关节 PVNS 患者在接受初次 THA 时是否经历了(1)更长的住院时间(LOS);(2)更多的并发症;(3)更高的再入院率;和(4)更高的成本。

方法

使用全国性的索赔登记处,确定了 2005 年至 2014 年期间因髋关节 PVNS 接受初次 THA 的患者。通过年龄、性别和各种合并症,将 PVNS 患者与对照组以 1:5 的比例进行匹配。查询共确定了 7440 名接受(n=1240)和未接受(n=6200)髋关节 PVNS 初次 THA 的患者。分析的终点包括 LOS、并发症、再入院率和成本。多变量逻辑回归用于确定发生并发症的比值比(OR)。使用 Welch's t 检验检验两组间 LOS 和成本的显著性。P 值小于 0.001 被认为具有统计学意义。

结果

PVNS 患者的住院时间平均延长了约 8%(3.8 天 vs 3.5 天,P=0.0006)。PVNS 患者发生医疗相关并发症(OR 1.60,P<0.0001)和植入物相关并发症(OR 1.81,P<0.0001)的几率更高。此外,PVNS 患者 90 天再入院的几率更高(OR 1.84,P<0.0001)。PVNS 患者手术当天的费用($13119 美元 vs $11983 美元,P<0.0001)和 90 天的费用($17169 美元 vs $15097 美元,P<0.0001)也更高。

结论

在未控制 2005 年至 2014 年期间 LOS、并发症、再入院率和成本的全球趋势的情况下,本研究的结果表明,髋关节 PVNS 与初次 THA 后更差的结果和更高的成本相关。该研究具有实际意义,因为骨科医生可以使用该研究向接受髋关节手术的患者告知可能发生的并发症。

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