Division of Infectious Diseases, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea.
Division of Pulmonology, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea.
Transbound Emerg Dis. 2021 Jul;68(4):2059-2065. doi: 10.1111/tbed.13853. Epub 2020 Oct 6.
To curb the COVID-19 pandemic, isolation measures are required. Shared room occupancy is recommended when isolation rooms are insufficient. However, there is little evidence of the applicability of shared and single room occupancy for patients with COVID-19 to determine whether shared room occupancy is feasible. COVID-19-infected patients admitted to the Daegu Dongsan Hospital of Keimyung University from 21 February 2020 to 20 April 2020 were enrolled in the study and randomly assigned to hospital rooms. Clinical symptoms, underlying diseases and epidemiological data of patients were analysed after dividing participants into a shared room occupancy group (group A) and a single room occupancy group (group B). Outcomes analysed included microbiological cure rates, time to clinical symptom improvement, time to defervescence and negative-to-positive conversion rates of polymerase chain reaction (PCR) results during hospitalization. A total of 666 patients were included in this study, 535 and 131 patients in groups A and B, respectively. Group B included more underlying conditions, such as pregnancy and solid organ transplantation, and was more closely associated with severe pneumonia during hospitalization. Besides, no statistically significant differences between the two groups in terms of negative PCR rates at HD 7 and 14, conversion rates of PCR results from negative-to-positive, as well as time to the improvement of clinical symptoms, and time to defervescence were observed. Our results suggest that the shared room occupancy of patients with mild symptoms could be an alternative to single room occupancy during the COVID-19 pandemic.
为了遏制 COVID-19 大流行,需要采取隔离措施。当隔离室不足时,建议共享房间入住。然而,对于 COVID-19 患者,共享和单人房入住的适用性证据很少,无法确定共享房入住是否可行。本研究纳入了 2020 年 2 月 21 日至 2020 年 4 月 20 日期间入住启明大学大邱东山医院的 COVID-19 感染患者,并将其随机分配到医院病房。分析了患者的临床症状、基础疾病和流行病学数据,将参与者分为共享房入住组(A 组)和单人房入住组(B 组)。分析的结果包括微生物学治愈率、临床症状改善时间、退热时间和住院期间聚合酶链反应(PCR)结果由阴转阳的转化率。本研究共纳入 666 例患者,A 组和 B 组分别为 535 例和 131 例。B 组包括更多的基础疾病,如妊娠和实体器官移植,并且在住院期间更密切地与重症肺炎相关。此外,两组在第 7 天和第 14 天的阴性 PCR 率、PCR 结果由阴转阳的转化率、临床症状改善时间和退热时间方面均无统计学差异。我们的结果表明,对于轻症患者,共享房入住可以作为 COVID-19 大流行期间单人房入住的替代方案。