Department of Internal Medicine, Seoul National University College of Medicine, 101 Daehak-ro Jongno-gu, Seoul, 03080, Republic of Korea.
Infection Control Office, Seoul National University Hospital, Seoul, Republic of Korea.
Antimicrob Resist Infect Control. 2024 Aug 30;13(1):95. doi: 10.1186/s13756-024-01454-w.
There is an ongoing controversy regarding whether single-occupancy rooms are superior to multiple-occupancy rooms in terms of infection prevention. We investigated whether treatment in a multiple-occupancy room is associated with an increased incidence of nosocomial coronavirus disease 2019 (COVID-19) compared with treatment in a single-occupancy room.
In this retrospective cohort study, every hospitalization period of adult patients aged ≥ 18 years at a tertiary hospital in Korea from January 1, 2022, to December 31, 2022, was analyzed. If COVID-19 was diagnosed more than 5 days after hospitalization, the case was classified as nosocomial. We estimated the association between the number of patients per room and the risk of nosocomial COVID-19 using a Cox proportional hazards regression model.
In total, 25,143 hospitalizations per room type were analyzed. The incidence rate of nosocomial COVID-19 increased according to the number of patients per room; it ranged from 3.05 to 38.64 cases per 10,000 patient-days between single- and 6-bed rooms, respectively. Additionally, the hazard ratios of nosocomial COVID-19 showed an increasing trend according to the number of patients per room, ranging from 0.14 (95% confidence interval 0.001-1.03) to 2.66 (95% confidence interval 1.60-4.85) between single- and 6-bed rooms, respectively.
We demonstrated that the incidence of nosocomial COVID-19 increased according to the number of patients per room. To reduce nosocomial infections by respiratory viruses, the use of multiple-occupancy rooms should be minimized.
关于单人间与多人间在预防感染方面的优劣，目前仍存在争议。本研究旨在调查与单人间相比，多人间治疗是否会增加医院获得性 2019 年冠状病毒病（COVID-19）的发病率。
本回顾性队列研究分析了 2022 年 1 月 1 日至 2022 年 12 月 31 日期间韩国一家三级医院≥18 岁成年患者的每例住院期。如果 COVID-19 在住院后 5 天以上被诊断，则将该病例归类为医院获得性。我们使用 Cox 比例风险回归模型估计每间病房患者人数与医院获得性 COVID-19 风险之间的关联。
共分析了 25143 例单人间和多人间住院情况。医院获得性 COVID-19 的发病率随每间病房患者人数的增加而增加；单人间和 6 人间的发病率分别为每 10000 患者日 3.05 至 38.64 例。此外，医院获得性 COVID-19 的风险比也随每间病房患者人数的增加呈上升趋势，单人间和 6 人间分别为 0.14（95%置信区间 0.001-1.03）至 2.66（95%置信区间 1.60-4.85）。
我们证实了医院获得性 COVID-19 的发病率随每间病房患者人数的增加而增加。为了减少呼吸道病毒引起的医院感染，应尽量减少多人间的使用。
