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[不育与不孕的免疫学方面]

[Immunologic aspects of sterility and infertility].

作者信息

Mettler L

出版信息

Immun Infekt. 1987 Apr;15(2):41-55.

PMID:3298016
Abstract

In the complex field of reproductive immunology, related disciplines overlap. Beyond the normal projects of family planning and sterility diagnosis and treatment, new possibilities of population control and early detection of chromosomal and genetic anomalies are pointed out. After a short introduction to the topic of sterility and infertility, the immunoregulatory mechanisms during physiological and pathological pregnancies are discussed. The antigenicity in the female and male reproductive tract and of the gametes themselves are described in detail. Various methods for sperm-antibody detection are compared, especially, a radioimmunoassay developed by the authors.

摘要

在生殖免疫学这个复杂领域中,相关学科相互重叠。除了计划生育以及不育症诊断与治疗这些常规项目外,还指出了人口控制以及染色体和基因异常早期检测的新可能性。在对不育和不孕主题进行简短介绍后,讨论了生理和病理妊娠期间的免疫调节机制。详细描述了女性和男性生殖道以及配子本身的抗原性。比较了各种精子抗体检测方法,尤其是作者开发的一种放射免疫测定法。

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