Internal Medicine Unit, Department of Medicine, Ospedale di Circolo di Rho, ASST Rhodense, Milan, Italy.
Internal Medicine Unit, Department of Medicine, Ospedale di Circolo di Rho, ASST Rhodense, Milan, Italy.
J Hosp Infect. 2020 Dec;106(4):709-712. doi: 10.1016/j.jhin.2020.08.027. Epub 2020 Sep 24.
At present, the time-frame used for the quarantine of individuals with coronavirus disease 2019 (COVID-19) is the entire duration of symptoms plus 14 days after symptom recovery; however, no data have been reported specifically for healthcare workers (HCWs). In the study population of 142 HCWs with COVID-19, the mean time for viral clearance was 31.8 days. Asymptomatic subjects cleared the virus more quickly than symptomatic subjects (22 vs 34.2 days; P<0.0001). The presence of fever at the time of diagnosis was associated with a longer time to viral clearance (relative risk 11.45, 95% confidence interval 8.66-14.25; P<0.0001). These findings may have a significant impact on healthcare strategies for the future management of the COVID-19 pandemic.
目前，针对 2019 冠状病毒病（COVID-19）患者的隔离时间框架为症状出现后的整个持续时间加上症状恢复后的 14 天；然而，尚未有专门针对医护人员（HCW）的报告。在 142 名 COVID-19 医护人员的研究人群中，病毒清除的平均时间为 31.8 天。无症状患者比有症状患者清除病毒的速度更快（22 天对 34.2 天；P<0.0001）。诊断时发热的存在与病毒清除时间延长相关（相对风险 11.45，95%置信区间 8.66-14.25；P<0.0001）。这些发现可能对未来 COVID-19 大流行管理的医疗保健策略产生重大影响。
