Nayler W G
Int J Cardiol. 1987 Jun;15(3):267-85. doi: 10.1016/0167-5273(87)90332-9.
Recent laboratory studies have shown that the calcium antagonists (slow channel blockers) can protect the myocardium against the consequences of experimentally induced ischemia and reperfusion. With one recent exception, however, clinical trials relating to the effectiveness of these drugs in the management of patients with myocardial infarction have been disappointing. This paper explores this apparent discrepancy.
近期的实验室研究表明，钙拮抗剂（慢通道阻滞剂）可保护心肌免受实验性诱导的缺血和再灌注后果的影响。然而，除了最近的一个例外，有关这些药物在心肌梗死患者治疗中有效性的临床试验一直令人失望。本文探讨了这一明显的差异。
