Tsuboi Hajime, Miyamori Daisuke, Ishikawa Noboru, Ichioka Hiroaki, Ikegaya Hiroshi
Department of Forensic Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Department of General Medicine, Graduate School of Medical Science, Hiroshima University, Hiroshima, Japan.
SAGE Open Med. 2020 Sep 16;8:2050312120958212. doi: 10.1177/2050312120958212. eCollection 2020.
An increase in number of unidentified cadavers is a growing problem. To identify these cadavers, a simple objective method is required to estimate cadaveric age. We examined the correlations between postmortem serum prostate-specific antigen levels and cadaveric age to determine whether serum prostate-specific antigen levels can be used in age estimation of unidentified cadavers.
Total serum prostate-specific antigen was measured in 140 male autopsy cases aged from 0 to 94 years.
The serum prostate-specific antigen levels of cadavers correlated with age at death to the same degree as with the age of living individuals (r = 0.393, < 0.01). Prostate-specific antigen levels also correlated with prostate weight, but not with psoas muscle index and body mass index. Cause of death did not influence postmortem serum prostate-specific antigen levels.
Age estimation based on prostate-specific antigen provides a simple, objective, and rapid method to determine age at death estimation of cadavers, and is expected to greatly contribute to the identification of cadavers.
身份不明尸体数量的增加是一个日益严重的问题。为了识别这些尸体，需要一种简单客观的方法来估计尸体年龄。我们研究了死后血清前列腺特异性抗原水平与尸体年龄之间的相关性，以确定血清前列腺特异性抗原水平是否可用于身份不明尸体的年龄估计。
在140例年龄从0至94岁的男性尸检病例中测量了血清总前列腺特异性抗原。
尸体的血清前列腺特异性抗原水平与死亡年龄的相关性与与在世个体年龄的相关性程度相同（r = 0.393，<0.01）。前列腺特异性抗原水平也与前列腺重量相关，但与腰大肌指数和体重指数无关。死因不影响死后血清前列腺特异性抗原水平。
基于前列腺特异性抗原的年龄估计提供了一种简单、客观且快速的方法来确定尸体的死亡年龄估计，有望对尸体识别做出巨大贡献。
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