Department of Internal Medicine and Immunology, Adana City Education and Research Hospital, Yüreğir, Turkey.
Department of Internal Medicine and Haematology, Adana City Education and Research Hospital, Yüreğir, Turkey.
Scand J Clin Lab Invest. 2020 Dec;80(8):649-653. doi: 10.1080/00365513.2020.1827288. Epub 2020 Sep 28.
The neutrophil-lymphocyte ratio is a simple and easily used parameter for the assessment of inflammation. We aimed to determine the predictive potential of the neutrophil-lymphocyte ratio regarding episode occurrence in patients with hereditary angioedema. Sixty-six patients with Type 1 hereditary angioedema and 60 healthy controls were included in the study. The laboratory results of the patients in their episode-free periods were similar to those of the healthy controls. The median of neutrophil-lymphocyte ratio was higher during episodes when compared to normal periods (3.5 versus 2.0, < .001). A significant positive correlation was present between the episode count and the neutrophil-lymphocyte ratio calculated during the episodes ( = 0.557, < .001). We can conclude that the neutrophil-lymphocyte ratio, which is cheap and easy to calculate, can be used by clinicians as a predictive parameter for prediction of the episode count in patients with hereditary angioedema.
中性粒细胞与淋巴细胞比值是评估炎症的一种简单且易于使用的参数。我们旨在确定中性粒细胞与淋巴细胞比值对遗传性血管性水肿患者发作的预测潜力。本研究纳入了 66 例 1 型遗传性血管性水肿患者和 60 名健康对照者。在无发作期间，患者的实验室结果与健康对照者相似。与正常时期相比，发作期间的中性粒细胞与淋巴细胞比值中位数更高（3.5 比 2.0， < .001）。发作期间计算的中性粒细胞与淋巴细胞比值与发作次数之间存在显著正相关（ = 0.557， < .001）。我们可以得出结论，中性粒细胞与淋巴细胞比值既便宜又易于计算，临床医生可以将其用作预测遗传性血管性水肿患者发作次数的预测参数。
