C57BL/6 小鼠胚胎成纤维样细胞培养中增殖活性的 infradian 节律。
Infradian Rhythm in Proliferative Activity of a Culture of Embryonic Fibroblast-Like Cells from C57BL/6 Mice.
机构信息
Research Institute of Human Morphology, Moscow, Russia.
A. N. Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences, Moscow, Russia.
出版信息
Bull Exp Biol Med. 2020 Sep;169(5):714-717. doi: 10.1007/s10517-020-04962-y. Epub 2020 Sep 28.
We studied daily dynamics of proliferative activity of embryonic fibroblast-like cells in culture during the logarithmic growth phase. Daily increase in cell count in the culture showed a 4-day rhythm that persisted over 3 weeks of culturing. In cultures from different animals, the phase of this rhythm was synchronous and did not depend on the moment of cell isolation. It can be hypothesized that the 4-day biorhythm of proliferative activity of embryonic fibroblast-like cells in culture is determined by external environmental factors, probably of electromagnetic nature.
我们研究了对数生长期培养的胚胎成纤维样细胞增殖活性的日动态变化。培养物中细胞计数的日增加显示出持续 3 周培养的 4 天节律。在来自不同动物的培养物中，该节律的相位是同步的，不依赖于细胞分离的时间。可以假设，培养中胚胎成纤维样细胞增殖活性的 4 天生物节律是由外部环境因素决定的，可能具有电磁性质。
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