Diatroptov M E, Diatroptova M A
A. N. Severtsov Institute of Ecology and Evolution, Russian Academy of Science, Moscow, Russia.
A. P. Avtsyn Research Institute of Human Morphology, B. V. Petrovsky National Research Centre of Surgery, Moscow, Russia.
Bull Exp Biol Med. 2023 Sep;175(5):685-689. doi: 10.1007/s10517-023-05926-8. Epub 2023 Oct 20.
The multi-day dynamics of the intensity of K decay fluctuations was compared with motor activity of laboratory mice, circulating cortisol in rabbits, and proliferation of fibroblast-like cultured cells L-929. A positive correlation was established between the intensity of decay fluctuations on the one hand, and total daily motor activity in mice and plasma cortisol level in rabbits, on the other hand. In addition, a negative correlation was observed between K decay fluctuations and proliferative activity of the cultured cells. Interestingly, these close correlations were observed not only against the background 4-day rhythm, but also in the time when any rhythmicity was absent. Thus, the intensity of K decay fluctuations is an indicator of a biotropic environmental factor that augments motor activity and raises the circulating cortisol in animals and down-regulates proliferation of cultured cells.
将钾衰变波动强度的多日动态与实验室小鼠的运动活动、兔子体内循环的皮质醇以及成纤维细胞样培养细胞L-929的增殖进行了比较。一方面，衰变波动强度与小鼠的每日总运动活动以及兔子的血浆皮质醇水平之间建立了正相关。此外，观察到钾衰变波动与培养细胞的增殖活性之间呈负相关。有趣的是，这些密切的相关性不仅在4天节律的背景下观察到，而且在没有任何节律性的时间段也观察到。因此，钾衰变波动强度是一种生物活性环境因子的指标，该因子可增强动物的运动活动、提高其循环皮质醇水平，并下调培养细胞的增殖。
