Dhillon Jasreman
Department of Anatomic Pathology, Moffitt Cancer Center, Tampa, Florida, USA,
Department of Oncologic Sciences and Pathology, University of South Florida, Tampa, Florida, USA,
Monogr Clin Cytol. 2020;26:92-108. doi: 10.1159/000455737. Epub 2020 Sep 28.
Non-ductal tumors of the pancreas are relatively rare tumors and include pancreatic neuroendocrine tumors (PanNETs), poorly differentiated neuroendocrine carcinomas, acinar cell carcinoma, solid pseudopapillary neoplasm, and pancreatoblastoma. These tumors have a morphology and biology that is distinct from that of ductal neoplasms of the pancreas. PanNETs are the most common tumors among this group. A brief summary of each tumor is described here with an emphasis on the clinical presentation, cytological features, tumor histology, and immunohistochemical profile. Differential diagnoses for each entity are also discussed.
胰腺非导管性肿瘤是相对罕见的肿瘤，包括胰腺神经内分泌肿瘤（PanNETs）、低分化神经内分泌癌、腺泡细胞癌、实性假乳头状瘤和胰母细胞瘤。这些肿瘤的形态和生物学特性与胰腺导管性肿瘤不同。PanNETs是该组中最常见的肿瘤。此处对每种肿瘤进行简要概述，重点介绍临床表现、细胞学特征、肿瘤组织学和免疫组化特征。还讨论了每种实体的鉴别诊断。
