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单次注射超声引导下椎板后椎旁阻滞用于乳腺手术的镇痛效果:一项前瞻性、随机、双盲研究。

The analgesic efficacy of a single injection of ultrasound-guided retrolaminar paravertebral block for breast surgery: a prospective, randomized, double-blinded study.

作者信息

Hwang Boo-Young, Kim Eunsoo, Kwon Jae-Young, Lee Ji-Youn, Lee Dowon, Park Eun Ji, Kang Taewoo

机构信息

Department of Anesthesia and Pain Medicine, Pusan National University School of Medicine, Yangsan, Korea.

Department of Anesthesia and Pain Medicine, Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.

出版信息

Korean J Pain. 2020 Oct 1;33(4):378-385. doi: 10.3344/kjp.2020.33.4.378.

DOI:10.3344/kjp.2020.33.4.378
PMID:32989202
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7532298/
Abstract

BACKGROUND

The thoracic paravertebral block is an effective analgesic technique for postoperative pain management after breast surgery. The ultrasound-guided retrolaminar block (RLB) is a safer alternative to conventional paravertebral block. Thus, we assessed the analgesic efficacy of ultrasound-guided RLB for postoperative pain management after breast surgery.

METHODS

Patients requiring breast surgery were randomly allocated to group C (retrolaminar injection with saline) and group R (RLB with local anesthetic mixture). The RLB was performed at the level of T3 with local anesthetic mixture (0.75% ropivacaine 20 mL + 2% lidocaine 10 mL) under general anesthesia before the skin incision. The primary outcome was cumulative morphine consumption using intravenous patient-controlled analgesia (IV-PCA) at 24 hour postoperatively. The secondary outcomes were the visual analogue scale (VAS) scores at 1, 6, 24, and 48 hour postoperatively and the occurrence of adverse events and patient satisfaction after the surgery.

RESULTS

Forty-six patients were included, 24 in group C and 22 in group R. The cumulative morphine consumption using IV-PCA did not differ between the two groups ( = 0.631). The intraoperative use of remifentanil was higher in group C than in group R ( = 0.025). The resting and coughing VAS scores at 1 hour postoperatively were higher in group R than in group C ( = 0.011, = 0.004). The incidence of adverse events and patient satisfaction was not significantly different between the two groups.

CONCLUSIONS

A single injection of ultrasound-guided RLB did not reduce postoperative analgesic requirements following breast surgery.

摘要

背景

胸段椎旁阻滞是乳房手术后疼痛管理的一种有效镇痛技术。超声引导下椎板后阻滞(RLB)是传统椎旁阻滞更安全的替代方法。因此,我们评估了超声引导下RLB用于乳房手术后疼痛管理的镇痛效果。

方法

需要进行乳房手术的患者被随机分配至C组(椎板后注射生理盐水)和R组(注射局部麻醉混合液进行RLB)。在全身麻醉下皮肤切开前,于T3水平使用局部麻醉混合液(0.75%罗哌卡因20 mL + 2%利多卡因10 mL)进行RLB。主要结局指标是术后24小时使用静脉自控镇痛(IV-PCA)时吗啡的累积用量。次要结局指标是术后1、6、24和48小时的视觉模拟评分(VAS)、不良事件的发生情况以及术后患者满意度。

结果

纳入46例患者,C组24例,R组22例。两组间使用IV-PCA时吗啡的累积用量无差异( = 0.631)。C组术中瑞芬太尼的使用量高于R组( = 0.025)。术后1小时R组静息和咳嗽时的VAS评分高于C组( = 0.011, = 0.004)。两组间不良事件发生率和患者满意度无显著差异。

结论

单次超声引导下RLB并不能减少乳房手术后的镇痛需求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5638/7532298/c8dc8d072cd9/KJP-33-378-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5638/7532298/7929ad356942/KJP-33-378-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5638/7532298/f0d0a10d017d/KJP-33-378-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5638/7532298/2b2bc141a950/KJP-33-378-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5638/7532298/c8dc8d072cd9/KJP-33-378-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5638/7532298/7929ad356942/KJP-33-378-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5638/7532298/f0d0a10d017d/KJP-33-378-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5638/7532298/2b2bc141a950/KJP-33-378-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5638/7532298/c8dc8d072cd9/KJP-33-378-f4.jpg

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