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超声引导下双侧胸椎旁肌阻滞对小儿开胸心脏手术后镇痛效果的影响:一项随机对照双盲研究。

The effect of ultrasound-guided bilateral thoracic retrolaminar block on analgesia after pediatric open cardiac surgery: a randomized controlled double-blind study.

机构信息

Department of Anesthesia and Surgical Intensive Care, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Department of Anesthesia and Surgical Intensive Care, Faculty of Medicine, Portsaid University, Portsaid, Egypt.

出版信息

Korean J Anesthesiol. 2022 Jun;75(3):276-282. doi: 10.4097/kja.21466. Epub 2022 Jan 12.

Abstract

BACKGROUND

The thoracic retrolaminar block (TRLB) is a relatively new regional analgesia technique that can be used as an alternative to the thoracic paravertebral block. This study aimed to evaluate the postoperative analgesia effects of ultrasound-guided TRLB in children undergoing open cardiac surgery via median sternotomy incision.

METHODS

Sixty-six patients aged 2-8 years were recruited. In the TRLB group, 0.25% bupivacaine 0.4 ml/kg was injected into the retrolaminar space on both sides at the level of the T4 lamina. Patients in the control group were injected with 0.9% saline. The primary outcome measure was fentanyl consumption in the first 24 h post-extubation. The secondary outcome measures were the total intraoperative fentanyl consumption, postoperative modified objective pain score (MOPS), and time to extubation.

RESULTS

The total intraoperative fentanyl requirements and fentanyl consumption in the first 24 h post-extubation were significantly lower (P < 0.001) in the TRLB group (9.3 ± 1.2; 6.9 ± 2.1 μg/kg, respectively) than in the control group (12.5 ± 1.4; 16.6 ± 2.8, respectively). The median (Q1, Q3) time to extubation was significantly shorter (P < 0.001) in the TRLB group (2 [1, 3] h) than in the control group (6 [4.5, 6] h). The MOPS was significantly lower (P < 0.05) in the TRLB group than in the control group at 0, 2, 4, 8, 12 and 16 h post-extubation.

CONCLUSIONS

Bilateral ultrasound-guided TRLB is effective in providing postoperative analgesia in children undergoing open cardiac surgery via median sternotomy incision.

摘要

背景

胸椎旁后入路阻滞(TRLB)是一种相对较新的区域镇痛技术,可作为胸椎旁阻滞的替代方法。本研究旨在评估超声引导下 TRLB 在经胸骨正中切开行开胸心脏手术的儿童中的术后镇痛效果。

方法

共纳入 66 名 2-8 岁的患者。在 TRLB 组中,在 T4 椎板水平双侧向椎旁间隙注射 0.25%布比卡因 0.4ml/kg。对照组患者注射 0.9%生理盐水。主要观察指标为拔管后 24 小时内芬太尼的消耗量。次要观察指标为术中总芬太尼用量、术后改良客观疼痛评分(MOPS)和拔管时间。

结果

TRLB 组(9.3 ± 1.2;6.9 ± 2.1 μg/kg)术中芬太尼总用量和拔管后 24 小时内芬太尼消耗量均明显低于对照组(12.5 ± 1.4;16.6 ± 2.8,均 P < 0.001)。TRLB 组拔管时间中位数(Q1,Q3)明显短于对照组(2 [1,3] h 比 6 [4.5,6] h,均 P < 0.001)。拔管后 0、2、4、8、12 和 16 小时,TRLB 组的 MOPS 均明显低于对照组(均 P < 0.05)。

结论

双侧超声引导下 TRLB 可有效为经胸骨正中切开行开胸心脏手术的儿童提供术后镇痛。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d114/9171541/88c53823c9ad/kja-21466f1.jpg

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