Postgraduate Program in Structural and Functional Interactions in Rehabilitation, University of Marília (UNIMAR), Marília, Brazil.
Department of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Marília, Brazil.
Metab Syndr Relat Disord. 2021 Feb;19(1):32-38. doi: 10.1089/met.2020.0083. Epub 2020 Sep 28.
Metabolic syndrome (MS) comprises a cluster of risk factors for the development of cardiovascular diseases, which are among the leading causes of morbidity and mortality worldwide. Many studies have shown that neck circumference (NC) has validity in the measure of MS since it correlates positively with the traditional components. For these reasons, this study aimed at comparing waist circumference (WC) and NC for identifying MS parameters in patients treated at a cardiology unit. This study included 309 patients assisted in a Cardiology Unit. Biochemical and anthropometric parameters were evaluated. Correlations between neck and WC with anthropometric, biochemical, and atherogenic indices were evaluated. The diagnostic ability of neck and WC was assessed by using the receiver operating characteristics curve. The patients had a mean age of 57.2 years, and 56% were men. The diagnosis of MS was present in 48% of men and 39% of women. Neck and WC showed a positive correlation with each other, and both showed positive correlations with the criteria for MS. Moreover, NC showed a positive correlation with body mass index (BMI), insulin, homeostatic model assessment (HOMA)-β, and C-reactive protein. WC showed a positive correlation with BMI, HOMA of insulin resistance (HOMA-IR), and Castelli Index I. Both neck and WC showed the ability to identify the presence of the MS. Both neck and WC showed a significant correlation with several of the metabolic parameters, including some used as criteria for the diagnosis of MS. In addition, both measures demonstrated a good ability to predict MS, making these measures promising for screening patients with this syndrome.
代谢综合征（MS）包括一组心血管疾病发病风险因素，这些因素是全球发病率和死亡率的主要原因之一。许多研究表明，颈围（NC）在衡量 MS 方面具有有效性，因为它与传统成分呈正相关。出于这些原因，本研究旨在比较腰围（WC）和 NC ，以确定在心脏病学单位接受治疗的患者的 MS 参数。本研究纳入了 309 名在心脏病学单位接受治疗的患者。评估了生化和人体测量参数。评估了颈围和 WC 与人体测量、生化和动脉粥样硬化指数之间的相关性。使用接收者操作特征曲线评估颈围和 WC 的诊断能力。患者的平均年龄为 57.2 岁，其中 56%为男性。48%的男性和 39%的女性被诊断为 MS。颈围和 WC 彼此之间呈正相关，两者均与 MS 的标准呈正相关。此外，NC 与体重指数（BMI）、胰岛素、稳态模型评估（HOMA）-β和 C 反应蛋白呈正相关。WC 与 BMI、胰岛素抵抗的 HOMA（HOMA-IR）和 Castelli 指数 I 呈正相关。颈围和 WC 均具有识别 MS 存在的能力。颈围和 WC 均与多项代谢参数显著相关，包括一些用于诊断 MS 的标准。此外，这两种措施都表现出很好的预测 MS 的能力，这使得这些措施有望用于筛查患有这种综合征的患者。
