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创伤护理系统对成年创伤患者死亡率的影响:一项系统评价和荟萃分析方案

The effect of trauma care systems on the mortality of injured adult patients: A protocol for systematic review and meta-analysis.

作者信息

Jifang Wu, Liping Yang, Jing Zhu, Jie Song

机构信息

Trauma Center, The First People's Hospital of Lianyungang, Lianyungang, Jiangsu Province, China.

出版信息

Medicine (Baltimore). 2020 Sep 25;99(39):e22279. doi: 10.1097/MD.0000000000022279.

Abstract

PURPOSE

The aim of this study was to have a comprehensive evaluation of the effect of trauma care systems on the mortality of injured adult patients.

MATERIALS AND METHODS

This protocol established in this study has been reported following the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols. Web of Science, PubMed, EMBASE, Scopus, and the Cochrane Library were searched for all clinical trials evaluating the effect of trauma care systems on the mortality of injured adult patients until July 31, 2020. We will use a combination of Medical Subject Heading and free-text terms with various synonyms to search based on the eligibility criteria. Two investigators independently reviewed the included studies and extracted relevant data. The odds ratio (OR) and 95% confidence intervals (CIs) were used as effect estimate. I-square (I) test, substantial heterogeneity, sensitivity analysis, and publication bias assessment will be performed accordingly. Stata 15.0 and Review Manger 5.3 are used for meta-analysis and systematic review.

RESULTS

The results will be published in a peer-reviewed journal.

CONCLUSION

The results of this review will be widely disseminated through peer-reviewed publications and conference presentations. This evidence may also provide a comprehensive evaluation of the effect of trauma care systems on the mortality of injured adult patients.

REGISTRATION NUMBER

INPLASY202080058.

摘要

目的

本研究旨在全面评估创伤护理系统对成年受伤患者死亡率的影响。

材料与方法

本研究中制定的方案已按照系统评价和Meta分析方案的首选报告项目进行报告。检索了Web of Science、PubMed、EMBASE、Scopus和Cochrane图书馆,以查找截至2020年7月31日评估创伤护理系统对成年受伤患者死亡率影响的所有临床试验。我们将结合医学主题词和带有各种同义词的自由文本术语,根据纳入标准进行检索。两名研究人员独立审查纳入的研究并提取相关数据。比值比(OR)和95%置信区间(CI)用作效应估计值。将相应地进行I方(I²)检验、实质性异质性分析、敏感性分析和发表偏倚评估。使用Stata 15.0和Review Manger 5.3进行Meta分析和系统评价。

结果

结果将发表在同行评审期刊上。

结论

本综述的结果将通过同行评审出版物和会议报告广泛传播。该证据还可能对创伤护理系统对成年受伤患者死亡率的影响提供全面评估。

注册号

INPLASY202080058。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af0c/7523867/03af0b37a01b/medi-99-e22279-g002.jpg

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