Lou W H
Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Zhonghua Wai Ke Za Zhi. 2020 Oct 1;58(10):745-748. doi: 10.3760/cma.j.cn112139-20200515-00384.
The incidence of pancreatic neuroendocrine tumor is increasing gradually in recent years.There are still lots of debated issues in surgical management of this kind of tumor.Whether all small non-functional pancreatic neuroendocrine tumor need to be resected, whether primary and metastatic lesion need to be resected in metastatic disease, whether adjuvant therapy is necessary for resected tumor, whether enucleation is optimal for small pancreatic neuroendocrine tumor.Some data from real world study has provide primary answer to these questions.More high-quality study in the future will provide satisfactory answer.
近年来,胰腺神经内分泌肿瘤的发病率逐渐上升。在这类肿瘤的外科治疗方面仍存在许多有争议的问题。所有小的无功能性胰腺神经内分泌肿瘤是否都需要切除,转移性疾病中原发性和转移性病灶是否需要切除,切除后的肿瘤是否需要辅助治疗,剜除术对小的胰腺神经内分泌肿瘤是否是最佳选择。一些来自真实世界研究的数据已对这些问题给出了初步答案。未来更多高质量的研究将给出令人满意的答案。