从 中分离得到三个新的 -香豆酰基倍半萜。
Three new -coumaroylated sesquiterpenoids from .
机构信息
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, PR China.
Beijing Pharmaceutical Group University of Staff and Workers, Beijing, PR China.
出版信息
Nat Prod Res. 2022 May;36(9):2239-2245. doi: 10.1080/14786419.2020.1826481. Epub 2020 Sep 30.
Four -coumaroylated sesquiterpenoids (), including three new ones (, , and ), were isolated from the whole plants of . Their structures were established on the basis of comprehensive spectroscopic analysis and comparison with data reported in the literature. Compounds were evaluated for their antimycobacterial activities, and and were active against HRv with the MIC values of 19.6 ± 0.19 and 17.4 ± 0.12 μg/mL, respectively.
从全株中分离得到了四个四香豆酰基倍半萜（），包括三个新化合物（，和）。它们的结构是基于综合光谱分析和与文献报道的数据比较确定的。对化合物进行了抗分枝杆菌活性评价，化合物和对 HRv 具有活性，MIC 值分别为 19.6±0.19 和 17.4±0.12μg/mL。
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