Research Center for Child Mental Development, Chiba University, 1-8-1 Inohana Chuouku, Chiba, 260-8670, Japan.
Research Department of Clinical, Educational & Health Psychology, University College London, London, UK.
Trials. 2020 Sep 29;21(1):814. doi: 10.1186/s13063-020-04750-z.
One aim of an autism spectrum disorder (ASD) diagnosis is to obtain special support for the disorder, though this does not guarantee practical support. We developed a psychoeducational program using cognitive-behavioral therapy (CBT) and Aware and Care for my Autistic Traits (ACAT) for Japanese adolescents with high-functioning ASD and their parents.
This multisite study is a randomized controlled trial. In total, 24 participants will be assigned to the ACAT group and 24 to the treatment-as-usual (TAU) group. The ACAT group will receive a weekly 100-min session for 6 weeks, regular medical care, and one follow-up session. In this ongoing clinical trial, we will compare the scores of the measures recorded in the pre- and post-intervention stages between the ACAT and TAU groups. A total of 41 patients out of a target of 48 have participated in the trial to date. The primary outcome measure is the Autism Knowledge Questionnaire. Secondary outcome measures include Barriers to Access to Care Evaluation 3rd Edition, the Strengths and Difficulties Questionnaire, the Vineland Adaptive Behavior Scales second edition, the Parenting Resilience Elements Questionnaire, the General Health Questionnaire 12, and the Depression Self-Rating Scale for Children assessments, as well as an electroencephalographic recording.
It is expected that participants in the ACAT group will significantly increase their self-understanding and awareness of ASD symptoms compared to those in the TAU group. Additionally, the ACAT group is expected to exhibit improved social adaptation and mental health if children and parents are able to better understand the ASD characteristics through sessions. This intervention will contribute to the establishment of an effective evidence-based treatment strategy for adolescents with ASD.
UMIN Register 000029851 . Registered on January 06, 2018.
自闭症谱系障碍（ASD）诊断的一个目的是为该障碍获得特殊支持，尽管这并不能保证实际支持。我们为日本高功能 ASD 青少年及其父母开发了一个使用认知行为疗法（CBT）和 Aware和关爱自闭症特质（ACAT）的心理教育计划。
这是一项多中心随机对照试验。共有 24 名参与者将被分配到 ACAT 组，24 名参与者被分配到常规治疗组（TAU）。ACAT 组将接受每周 100 分钟的 6 周疗程、常规医疗护理和一次随访。在这项正在进行的临床试验中，我们将比较 ACAT 和 TAU 组在干预前后阶段记录的测量得分。迄今为止，已有 41 名患者参加了该试验，目标人数为 48 名。主要结局测量是自闭症知识问卷。次要结局测量包括障碍评估 3 版、困难问卷、韦氏儿童智力量表第二版、父母适应力元素问卷、一般健康问卷 12 项和儿童抑郁自评量表评估，以及脑电图记录。
预计与 TAU 组相比，ACAT 组的参与者将显著增加对 ASD 症状的自我理解和认识。此外，如果儿童和家长能够通过课程更好地了解 ASD 特征，ACAT 组预计将表现出更好的社会适应和心理健康。这项干预将有助于为 ASD 青少年建立有效的循证治疗策略。
UMIN 注册 000029851。注册于 2018 年 1 月 6 日。
