Suppr超能文献

古巴的 COVID-19 与癌症

COVID-19 and Cancer in Cuba.

机构信息

Cancer Control Division, Ministry of Health, La Habana, CP, Cuba.

Clinical Research Division, Center of Molecular Immunology, Havana, Cuba.

出版信息

Semin Oncol. 2020 Oct;47(5):328-329. doi: 10.1053/j.seminoncol.2020.07.009. Epub 2020 Aug 7.

Abstract

The COVID-19 pandemic has called attention to the contribution of comorbidities, including cancer and brought additional challenges to previously existing programs for cancer treatment and control. The COVID-19 pandemic in Cuba was addressed through an integrated all-society action plan that to date has been largely successful with a low incidence of COVID-19 and mortality rates several-fold lower than worldwide averages. Despite downsizing many other health components all oncology services were maintained. Between March 11, when the first case was detected, until July 23, Cuba reported 2,449 cases of COVID-19 that included 28 (1.14%) with a diagnosis of cancer. Distribution among cancer diagnoses did not deviate from that expected according to cancer epidemiology in Cuba. However, although the probability of getting infected with the coronavirus for a cancer patient (0.012%), was not higher than that of the general population (0.020%), 9 of the 28 (32.1%) died, a lethality higher than that of COVID-19 patients without cancer (3.5%) a difference that is statistically significant (P< .001). We argue that going forward scientific research on the relationship of aging, inflammation and cancer, including identification of biomarkers and the development of novel therapeutic interventions, should become one of the priorities in the post-COVID agenda of both oncologists and infectious disease scientists.

摘要

新型冠状病毒肺炎(COVID-19)大流行引起了人们对合并症(包括癌症)的关注,并给以前存在的癌症治疗和控制计划带来了额外的挑战。古巴通过一项综合的全社会行动计划应对 COVID-19 疫情,该计划迄今为止取得了很大成功,COVID-19 发病率低,死亡率比全球平均水平低数倍。尽管大幅削减了许多其他卫生部门的预算,但所有肿瘤学服务都得以维持。自 3 月 11 日首次发现病例至 7 月 23 日,古巴报告了 2449 例 COVID-19 病例,其中 28 例(1.14%)诊断为癌症。根据古巴的癌症流行病学,癌症诊断的分布与预期相符。然而,尽管癌症患者感染冠状病毒的概率(0.012%)并不高于普通人群(0.020%),但 28 例中有 9 例(32.1%)死亡,其死亡率高于无癌症的 COVID-19 患者(3.5%),差异具有统计学意义(P<.001)。我们认为,今后应将老龄化、炎症和癌症之间关系的科学研究,包括识别生物标志物和开发新的治疗干预措施,作为肿瘤学家和传染病学家在 COVID-19 后议程中的优先事项之一。

相似文献

1
COVID-19 and Cancer in Cuba.古巴的 COVID-19 与癌症
Semin Oncol. 2020 Oct;47(5):328-329. doi: 10.1053/j.seminoncol.2020.07.009. Epub 2020 Aug 7.
4
Management strategy for cancer patients in the context of the COVID-19 epidemic.COVID-19 疫情下癌症患者的管理策略。
Semin Oncol. 2020 Oct;47(5):312-314. doi: 10.1053/j.seminoncol.2020.07.004. Epub 2020 Jul 28.
10
Clinical trials and the COVID-19 pandemic.临床试验与新冠疫情
Hell J Nucl Med. 2020 Jan-Apr;23(1):4-5. doi: 10.1967/s002449912014.

本文引用的文献

6
Control of advanced cancer: the road to chronicity.晚期癌症的控制:走向慢性化。
Int J Environ Res Public Health. 2011 Mar;8(3):683-97. doi: 10.3390/ijerph8030683. Epub 2011 Mar 1.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验