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硅酸铌颗粒作为复合材料的生物活性填料。

Niobium silicate particles as bioactive fillers for composite resins.

机构信息

Dental Materials Laboratory, School of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

Yller Biomaterials SA- Straumann Group - Pelotas, RS, Brazil.

出版信息

Dent Mater. 2020 Dec;36(12):1578-1585. doi: 10.1016/j.dental.2020.09.010. Epub 2020 Sep 29.

Abstract

OBJECTIVES

This study aimed to evaluate the influence of niobium silicate (SiNb) particles in the physicomechanical and biological properties of an experimental composite resin.

METHODS

The SiNb particles were incorporated (50 wt%) into a polymeric matrix formulated with 70 wt% Bisphenol A-Glycidyl Methacrylate and 30 wt% Triethylene Glycol Dimethacrylate to formulate an experimental composite resin. A control group was formulated with barium silicate glass (SiBa) as filler for the same polymeric matrix. The composite resins were tested for their refractive index, polymerization kinetics, flexural strength, radiopacity, softening in solvent, pH, cytotoxicity and mineral deposition.

RESULTS

The SiBa group presented refractive index results between 1.50 and 1.52 and the SiNb between 1.43-1.45. No statistically significant difference in the degree of conversion, flexural strength, and softening in solvent was observed between different groups. Radiopacity was lower for SiNb, while the addition of these particles increased cell viability. The pH was increased for all groups after immersion. The mineral deposition analysis resulted in increased deposition above specimens after the immersion in SBF.

SIGNIFICANCE

Niobium silicate particles may be used as an alternative inorganic filler to achieve an adequate balance between physical-chemical and biological properties for the development of bioactive composite resins.

摘要

目的

本研究旨在评估硅铌(SiNb)颗粒对实验性复合树脂的物理力学和生物学性能的影响。

方法

将 SiNb 颗粒(50wt%)掺入到由双酚 A-缩水甘油甲基丙烯酸酯(70wt%)和三乙二醇二甲基丙烯酸酯(30wt%)组成的聚合物基质中,以制备实验性复合树脂。对照组用钡硅酸盐玻璃(SiBa)作为相同聚合物基质的填料进行配制。对复合树脂的折射率、聚合动力学、弯曲强度、射线不透性、溶剂软化、pH 值、细胞毒性和矿物质沉积进行测试。

结果

SiBa 组的折射率结果在 1.50 到 1.52 之间,而 SiNb 组在 1.43-1.45 之间。不同组之间的转化率、弯曲强度和溶剂软化程度没有统计学上的显著差异。SiNb 的射线不透性较低,而添加这些颗粒会增加细胞活力。所有组的 pH 值在浸泡后均升高。在 SBF 浸泡后,在标本上方进行矿物质沉积分析,结果表明沉积增加。

意义

硅铌颗粒可以用作替代无机填料,以在物理化学和生物学性能之间达到适当的平衡,从而开发出具有生物活性的复合树脂。

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