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胆碱能对建构能力和记忆过程的影响:一例报告

Cholinergic effects on constructional abilities and on mnemonic processes: a case report.

作者信息

Sahakian B, Joyce E, Lishman W A

出版信息

Psychol Med. 1987 May;17(2):329-33. doi: 10.1017/s0033291700024867.

DOI:10.1017/s0033291700024867
PMID:3299440
Abstract

The effects of physostigmine on test performance of a patient with multiple cognitive deficits were observed in a double-blind, placebo-controlled study. Scores on tests of learning and memory and tests of visuo-spatial and constructional ability were both improved by physostigmine, while lecithin improved scores only on the former tests.

摘要

在一项双盲、安慰剂对照研究中,观察了毒扁豆碱对一名患有多种认知缺陷患者测试表现的影响。毒扁豆碱使学习与记忆测试以及视觉空间和构建能力测试的分数均得到提高,而卵磷脂仅使前一类测试的分数得到提高。

相似文献

1
Cholinergic effects on constructional abilities and on mnemonic processes: a case report.胆碱能对建构能力和记忆过程的影响:一例报告
Psychol Med. 1987 May;17(2):329-33. doi: 10.1017/s0033291700024867.
2
Effects of physostigmine and lecithin on memory in Alzheimer disease.
Ann Neurol. 1979 Sep;6(3):219-21. doi: 10.1002/ana.410060307.
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No effect from double-blind trial of physostigmine and lecithin in Alzheimer disease.
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Differential responsivity of verbal and visual recognition memory to physostigmine and ACTH.言语和视觉识别记忆对毒扁豆碱和促肾上腺皮质激素的差异反应性。
Biol Psychiatry. 1986 May;21(5-6):538-42. doi: 10.1016/0006-3223(86)90196-4.
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Oral physostigmine and lecithin improve memory in Alzheimer disease.口服毒扁豆碱和卵磷脂可改善阿尔茨海默病患者的记忆力。
Ann Neurol. 1983 May;13(5):491-6. doi: 10.1002/ana.410130504.
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Effects of oral physostigmine and lecithin on memory and attention in closed head-injured patients.口服毒扁豆碱和卵磷脂对闭合性颅脑损伤患者记忆力和注意力的影响。
Cent Nerv Syst Trauma. 1986 Fall;3(4):333-42. doi: 10.1089/cns.1986.3.333.
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Cholinergic system and constructional praxis: a further study of physostigmine in Alzheimer's disease.胆碱能系统与结构性运用:毒扁豆碱在阿尔茨海默病中的进一步研究
J Neurol Neurosurg Psychiatry. 1984 May;47(5):485-91. doi: 10.1136/jnnp.47.5.485.
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Memory decline in the aged: treatment with lecithin and physostigmine.老年人记忆力衰退:卵磷脂和毒扁豆碱治疗
Neurology. 1982 Sep;32(9):944-50. doi: 10.1212/wnl.32.9.944.
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L-deprenyl and physostigmine for the treatment of Alzheimer's disease.左旋司来吉兰和毒扁豆碱用于治疗阿尔茨海默病。
Psychiatry Res. 1995 Oct 16;58(3):181-9. doi: 10.1016/0165-1781(95)02714-8.
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Oral administration of chronic physostigmine does not improve cognitive or mnesic performances in Alzheimer's presenile dementia.长期口服毒扁豆碱并不能改善早老性阿尔茨海默病痴呆患者的认知或记忆表现。
Int J Neurosci. 1982 May;16(3-4):247-9. doi: 10.3109/00207458209147153.

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Treatment effects in multiple cognitive domains in Alzheimer's disease: a two-year cohort study.阿尔茨海默病多认知领域的治疗效果:一项为期两年的队列研究。
Alzheimers Res Ther. 2014 Aug 18;6(4):48. doi: 10.1186/alzrt280. eCollection 2014.
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Cholinesterase inhibition modulates visual and attentional brain responses in Alzheimer's disease and health.胆碱酯酶抑制作用可调节阿尔茨海默病及健康状态下的视觉和注意力相关脑反应。
Brain. 2008 Feb;131(Pt 2):409-24. doi: 10.1093/brain/awm299. Epub 2007 Dec 12.
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Nimodipine for primary degenerative, mixed and vascular dementia.
尼莫地平用于原发性退行性、混合型和血管性痴呆。
Cochrane Database Syst Rev. 2000;2002(2):CD000147. doi: 10.1002/14651858.CD000147.
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The cognitive psychopharmacology of Alzheimer's disease: focus on cholinergic systems.阿尔茨海默病的认知神经药理学:聚焦胆碱能系统。
Neurochem Res. 1998 May;23(5):787-94. doi: 10.1023/a:1022419712453.
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The alpha(2) antagonist idazoxan remediates certain attentional and executive dysfunction in patients with dementia of frontal type.α₂拮抗剂伊达唑啉可改善额颞叶型痴呆患者的某些注意力和执行功能障碍。
Psychopharmacology (Berl). 1996 Feb;123(3):239-49. doi: 10.1007/BF02246578.