Kosal Margaret E
Orbis. 2020;64(4):599-614. doi: 10.1016/j.orbis.2020.08.008. Epub 2020 Sep 25.
At the intersection of emerging technologies and international affairs, one of the most provocative areas is the applications of advanced genetic engineering. The COVID-19 global pandemic and uncertainty about the origin of the causative virus illustrates both immediacy and the potential geopolitical implications of such technologies. These new gene editing techniques include one which has garnered a great deal of attention, the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) systems, as well as other, less well-known ones. CRISPR is not the first type of gene editing technology, but it is the most well-known within national and international security debates. Such advancements now allow for easier and more tunable manipulation of the genetic code of life with implications for governance of science and technology and with international security significance in the context of proliferation, deterrence, and unconventional weapons. Biosecurity and other emerging technologies require new models, not simple extrapolations of Cold War or more recent deterrence (or nonproliferation) paradigms.
在新兴技术与国际事务的交叉领域,最具争议性的领域之一是先进基因工程的应用。新冠疫情全球大流行以及致病病毒起源的不确定性,既体现了此类技术的紧迫性,也凸显了其潜在的地缘政治影响。这些新的基因编辑技术包括一种备受关注的技术——成簇规律间隔短回文重复序列(CRISPR)系统,以及其他一些不太知名的技术。CRISPR并非第一种基因编辑技术,但它在国内和国际安全辩论中最为知名。此类进展如今使得对生命遗传密码的操作更加容易且更具可调节性,这对科技治理具有影响,并且在扩散、威慑和非常规武器的背景下具有国际安全意义。生物安全和其他新兴技术需要新的模式,而不是简单地沿用冷战或最近的威慑(或防扩散)范式。