• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

肾移植患者的棘状毛发发育异常：成功治疗的病例报告

Trichodysplasia spinulosa in a renal transplant patient: A case report of successful treatment.

作者信息

Pennou Camille, Javidi Eileen, Lecours Julie, Bélisle Annie, Davar Sandra

机构信息

Department of Dermatology, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, QC, Canada.

Faculty of Medecine, Université de Montréal, Montréal, QC, Canada.

出版信息

SAGE Open Med Case Rep. 2020 Sep 18;8:2050313X20953039. doi: 10.1177/2050313X20953039. eCollection 2020.

DOI:10.1177/2050313X20953039
PMID:32995002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7502798/
Abstract

Trichodysplasia spinulosa is a rare cutaneous disease caused by the trichodysplasia spinulosa-associated polyomavirus. It occurs more frequently in immunocompromised patients, particularly in solid organ transplants. A few successful treatments have been described in the literature. In our report, we present a biopsy-proven trichodysplasia spinulosa case in a kidney transplant recipient who rapidly responded to a reduction of his immunosuppressive therapy.

摘要

棘状毛发发育异常是一种由棘状毛发发育异常相关多瘤病毒引起的罕见皮肤病。它在免疫功能低下的患者中更常见，尤其是实体器官移植患者。文献中描述了一些成功的治疗方法。在我们的报告中，我们展示了一例经活检证实的棘状毛发发育异常病例，该病例为一名肾移植受者，其对免疫抑制治疗的减少迅速产生了反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/829c/7502798/7b4bc49d340d/10.1177_2050313X20953039-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/829c/7502798/1341ccf0c9b5/10.1177_2050313X20953039-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/829c/7502798/149d8a5c80fa/10.1177_2050313X20953039-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/829c/7502798/f1ece2944e1e/10.1177_2050313X20953039-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/829c/7502798/d37f598af697/10.1177_2050313X20953039-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/829c/7502798/cac0ffbc53f3/10.1177_2050313X20953039-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/829c/7502798/33357a128abc/10.1177_2050313X20953039-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/829c/7502798/7b4bc49d340d/10.1177_2050313X20953039-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/829c/7502798/1341ccf0c9b5/10.1177_2050313X20953039-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/829c/7502798/149d8a5c80fa/10.1177_2050313X20953039-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/829c/7502798/f1ece2944e1e/10.1177_2050313X20953039-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/829c/7502798/d37f598af697/10.1177_2050313X20953039-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/829c/7502798/cac0ffbc53f3/10.1177_2050313X20953039-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/829c/7502798/33357a128abc/10.1177_2050313X20953039-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/829c/7502798/7b4bc49d340d/10.1177_2050313X20953039-fig7.jpg

相似文献

1
Trichodysplasia spinulosa in a renal transplant patient: A case report of successful treatment.肾移植患者的棘状毛发发育异常：成功治疗的病例报告
SAGE Open Med Case Rep. 2020 Sep 18;8:2050313X20953039. doi: 10.1177/2050313X20953039. eCollection 2020.
2
Trichodysplasia spinulosa: Case reports and review of literature.棘状毛发发育异常：病例报告及文献综述
Transpl Infect Dis. 2020 Oct;22(5):e13342. doi: 10.1111/tid.13342. Epub 2020 Jun 16.
3
Photodynamic therapy for the treatment of trichodysplasia spinulosa in an Asian renal transplant recipient: A case report and review of literature.光动力疗法治疗亚洲肾移植受者的棘状毛囊发育不良：一例报告及文献复习
JAAD Case Rep. 2020 Nov 17;7:74-83. doi: 10.1016/j.jdcr.2020.10.037. eCollection 2021 Jan.
4
Leflunomide for the treatment of trichodysplasia spinulosa in a liver transplant recipient.来氟米特用于治疗肝移植受者的棘状毛囊发育不良。
Transpl Infect Dis. 2017 Aug;19(4). doi: 10.1111/tid.12702. Epub 2017 May 15.
5
Sustained Trichodysplasia Spinulosa Polyomavirus Viremia Illustrating a Primary Disseminated Infection in a Kidney Transplant Recipient.持续性棘状毛滴虫样多瘤病毒血症：一例肾移植受者原发性播散性感染病例
Microorganisms. 2021 Nov 5;9(11):2298. doi: 10.3390/microorganisms9112298.
6
Trichodysplasia spinulosa in a child: Identification of trichodysplasia spinulosa-associated polyomavirus in skin, serum, and urine.一名儿童的棘状毛发发育异常：在皮肤、血清和尿液中鉴定出与棘状毛发发育异常相关的多瘤病毒
Pediatr Dermatol. 2019 Sep;36(5):723-724. doi: 10.1111/pde.13857. Epub 2019 Jun 12.
7
Trichodysplasia spinulosa mimicking lichen nitidus in a renal transplant patient.肾移植患者中表现为光泽苔藓的棘状毛发发育异常
Pediatr Transplant. 2019 Jun;23(4):e13394. doi: 10.1111/petr.13394. Epub 2019 Mar 27.
8
Viremia and viruria of trichodysplasia spinulosa-associated polyomavirus before the development of clinical disease in a kidney transplant recipient.在一名肾移植受者出现临床疾病之前，棘状毛囊发育不良相关多瘤病毒的病毒血症和病毒尿症。
Transpl Infect Dis. 2019 Aug;21(4):e13133. doi: 10.1111/tid.13133. Epub 2019 Jul 6.
9
Pediatric trichodysplasia spinulosa: A report of 2 cases and review of the literature.儿童棘状毛发发育异常：2例报告及文献复习
Pediatr Dermatol. 2020 Nov;37(6):1023-1029. doi: 10.1111/pde.14323. Epub 2020 Aug 12.
10
Trichodysplasia spinulosa: rare presentation of polyomavirus infection in immunocompromised patients.棘层松解性外毛根鞘瘤：免疫功能低下患者中多瘤病毒感染的罕见表现。
J Cutan Med Surg. 2014 Nov;18(6):430-5. doi: 10.2310/7750.2014.13189.

本文引用的文献

1
Widespread keratosis pilaris-like eruption in an immunocompromised child.一名免疫功能低下儿童出现广泛的毛发角化病样皮疹。
JAAD Case Rep. 2019 Apr 5;5(4):352-354. doi: 10.1016/j.jdcr.2019.02.001. eCollection 2019 Apr.
2
Polyomaviruses of the skin: integrating molecular and clinical advances in an emerging class of viruses.皮肤多瘤病毒：整合新兴病毒类别的分子和临床进展。
Br J Dermatol. 2019 Jun;180(6):1302-1311. doi: 10.1111/bjd.17592. Epub 2019 Mar 14.
3
Trichodysplasia spinulosa associated with HIV infection: clinical response to acitretin and valganciclovir.
与HIV感染相关的棘状毛发发育异常：阿维A和缬更昔洛韦的临床疗效
Clin Exp Dermatol. 2018 Mar;43(2):231-233. doi: 10.1111/ced.13286. Epub 2017 Oct 13.
4
Leflunomide for the treatment of trichodysplasia spinulosa in a liver transplant recipient.来氟米特用于治疗肝移植受者的棘状毛囊发育不良。
Transpl Infect Dis. 2017 Aug;19(4). doi: 10.1111/tid.12702. Epub 2017 May 15.
5
Trichodysplasia Spinulosa Polyomavirus Infection Occurs during Early Childhood with Intrafamilial Transmission, Especially from Mother to Child.棘状毛发育异常多瘤病毒感染在儿童早期发生，存在家庭内传播，尤其是从母亲传给孩子。
J Invest Dermatol. 2017 May;137(5):1181-1183. doi: 10.1016/j.jid.2016.12.017. Epub 2017 Jan 17.
6
Trichodysplasia Spinulosa in a 7-Year-Old Boy Managed Using Physical Extraction of Keratin Spicules.一名7岁男孩的棘状毛发发育异常，采用物理拔除角蛋白小刺进行治疗。
Pediatr Dermatol. 2017 Mar;34(2):e74-e76. doi: 10.1111/pde.13045. Epub 2016 Dec 19.
7
Primary Polyomavirus Infection, Not Reactivation, as the Cause of Trichodysplasia Spinulosa in Immunocompromised Patients.原发性多瘤病毒感染而非病毒再激活是免疫功能低下患者棘状毛囊发育不良的病因。
J Infect Dis. 2017 Apr 1;215(7):1080-1084. doi: 10.1093/infdis/jiw403.
8
Trichodysplasia spinulosa: A rare complication of immunosuppression.棘状毛发发育异常：免疫抑制的一种罕见并发症。
JAAD Case Rep. 2016 Aug 5;2(4):307-9. doi: 10.1016/j.jdcr.2016.07.002. eCollection 2016 Jul.
9
Two cases of trichodysplasia spinulosa responsive to compounded topical cidofovir 3% cream.两例对复方3%西多福韦外用乳膏有反应的棘状毛发病。
JAAD Case Rep. 2015 Nov 24;1(6):S33-5. doi: 10.1016/j.jdcr.2015.09.019. eCollection 2015 Nov.
10
Trichodysplasia spinulosa: a polyomavirus infection specifically targeting follicular keratinocytes in immunocompromised patients.毛发疏松性外毛根鞘瘤：一种多瘤病毒感染，主要针对免疫功能低下患者的毛囊角质形成细胞。
Br J Dermatol. 2016 Mar;174(3):629-32. doi: 10.1111/bjd.14346. Epub 2016 Jan 28.