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小剂量氨磺必利引发的神经阻滞剂恶性综合征

Neuroleptic Malignant Syndrome with Minimal Dose of Amisulpride.

作者信息

Raj Kishan, Jajor T R, Khandelwal Ashish, Goyal Gaurav

机构信息

Institute of Brain and Spine Faridabad Consultant Neurology Haryana India.

Institute of Brain and Spine Faridabad Consultant Psychiatry Haryana India.

出版信息

J Acute Med. 2017 Sep 1;7(3):122-124. doi: 10.6705/j.jacme.2017.0703.005.

Abstract

Amisulpride is an atypical antipsychotic drug, it helps in alleviation of symptoms of psychotic illnesses. Extrapyramidal features have been reported after taking amisulpride. Neuroleptic malignant syndrome (NMS) with amisulpride is rare, and have been reported earlier. In all the earlier reported cases patient received more than 150 mg of amisulpride. To the best of our knowledge we are reporting a case of NMS with very minimal dose of Amisulpride (50 mg) taken for very short period.

摘要

氨磺必利是一种非典型抗精神病药物,有助于缓解精神病性疾病的症状。服用氨磺必利后曾有锥体外系反应的报道。氨磺必利所致的神经阻滞剂恶性综合征(NMS)较为罕见,此前已有报道。在所有先前报道的病例中,患者服用的氨磺必利超过150毫克。据我们所知,我们正在报告一例服用极低剂量(50毫克)氨磺必利且服用时间极短的NMS病例。

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Pharmacoepidemiol Drug Saf. 2010 May;19(5):429-35. doi: 10.1002/pds.1937.
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Amisulpride-induced neuroleptic malignant syndrome.氨磺必利诱发的抗精神病药恶性综合征。
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