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Formative development of a fertility decision aid for transgender adolescents and young adults: a multidisciplinary Delphi consensus study.生育决策辅助工具在跨性别青少年和年轻成人中形成性发展的多学科德尔菲共识研究。
J Assist Reprod Genet. 2020 Nov;37(11):2805-2816. doi: 10.1007/s10815-020-01947-8. Epub 2020 Sep 30.
2
Factors Affecting Fertility Decision-Making Among Transgender Adolescents and Young Adults.影响跨性别青少年和青年生育决策的因素。
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Transgender and Gender Diverse Fertility Choices: Supporting the Decision-Making Process for Adolescents and Young Adults.跨性别和性别多样化的生育选择：支持青少年和年轻成年人的决策过程。
J Pediatr. 2022 Jan;240:256-264.e1. doi: 10.1016/j.jpeds.2021.10.013. Epub 2021 Oct 28.
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Health care provider perceptions of fertility preservation barriers and challenges with transgender patients and families: qualitative responses to an international survey.医疗保健提供者对跨性别患者及其家庭的生育力保存障碍和挑战的看法：对国际调查的定性回应。
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Reproductive Health in Trans and Gender Diverse Patients: Fertility related knowledge, attitudes, and decision-making among gender diverse youth - A narrative review.跨性别和性别多样化患者的生殖健康：性别多样化青年的生育相关知识、态度和决策 - 叙述性综述。
Reproduction. 2024 Jun 21;168(2). doi: 10.1530/REP-24-0032. Print 2024 Aug 1.
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Fertility preservation decision making amongst Australian transgender and non-binary adults.澳大利亚跨性别和非二元成年人的生育力保存决策。
Reprod Health. 2018 Oct 25;15(1):181. doi: 10.1186/s12978-018-0627-z.
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Fertility preservation for transgender adolescents and young adults: a systematic review. transgender 青少年和年轻人的生育力保存：系统评价。
Hum Reprod Update. 2019 Nov 5;25(6):694-716. doi: 10.1093/humupd/dmz026.
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Transgender persons' view on previous fertility decision-making and current infertility: a qualitative study.跨性别者对先前生育决策和当前不孕的看法：一项定性研究。
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Access, barriers, and decisional regret in pursuit of fertility preservation among transgender and gender-diverse individuals.寻求生育力保存的跨性别和性别多样化个体的可及性、障碍和决策后悔。
Fertil Steril. 2021 Apr;115(4):1029-1034. doi: 10.1016/j.fertnstert.2020.09.007. Epub 2020 Dec 1.
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Co-design and usability of an interactive web-based fertility decision aid for transgender youth and young adults.为跨性别青少年和年轻人设计的基于网络的交互式生育决策辅助工具的协同设计与可用性
J Pediatr Psychol. 2025 Jan 1;50(1):40-50. doi: 10.1093/jpepsy/jsae032.

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Patient education and counselling of fertility preservation for transgender and gender diverse people: A scoping review.跨性别者和性别多样化人群生育力保存的患者教育与咨询：一项范围综述
Paediatr Child Health. 2023 Jul 19;29(4):231-237. doi: 10.1093/pch/pxad050. eCollection 2024 Jul.
2
Co-design and usability of an interactive web-based fertility decision aid for transgender youth and young adults.为跨性别青少年和年轻人设计的基于网络的交互式生育决策辅助工具的协同设计与可用性
J Pediatr Psychol. 2025 Jan 1;50(1):40-50. doi: 10.1093/jpepsy/jsae032.
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Fertility counseling guide for transgender and gender diverse people.跨性别者和性别多元者的生育咨询指南。
Int J Transgend Health. 2023 Sep 12;24(4):361-367. doi: 10.1080/26895269.2023.2257062. eCollection 2023.
4
Reproductive and Fertility Knowledge and Attitudes Among Transgender and Gender-Expansive Youth: A Replication and Extension.跨性别和性别多样化青年的生殖与生育知识及态度：一项重复与扩展研究
Transgend Health. 2023 Jul 28;8(4):328-336. doi: 10.1089/trgh.2021.0080. eCollection 2023 Aug.
5
Fertility preservation in transgender men and the need for uniform, comprehensive counseling.跨性别男性的生育力保存及统一、全面咨询的必要性。
F S Rep. 2022 Jul 19;3(3):253-263. doi: 10.1016/j.xfre.2022.07.006. eCollection 2022 Sep.

本文引用的文献

1
Timing and Delivery of Fertility Preservation Information to Transgender Adolescents, Young Adults, and Their Parents.向跨性别青少年、青年及其父母提供生育力保存信息的时机和方式。
J Adolesc Health. 2021 Mar;68(3):619-622. doi: 10.1016/j.jadohealth.2020.06.044. Epub 2020 Aug 18.
2
Attitudes Toward Fertility Preservation Among Transgender Youth and Their Parents. transgender 青少年及其父母对生育力保存的态度。
J Adolesc Health. 2020 Oct;67(4):583-589. doi: 10.1016/j.jadohealth.2020.02.027. Epub 2020 Apr 29.
3
Fertility Counseling for Transgender Adolescents: A Review.为跨性别青少年提供生育咨询：综述
J Adolesc Health. 2020 Jun;66(6):658-665. doi: 10.1016/j.jadohealth.2020.01.007. Epub 2020 Feb 27.
4
The "Begin Exploring Fertility Options, Risks and Expectations" (BEFORE) decision aid: development and alpha testing of a fertility tool for premenopausal breast cancer patients.《开始探索生育选择、风险和期望》（BEFORE）决策辅助工具：用于绝经前乳腺癌患者的生育工具的开发和初步测试。
BMC Med Inform Decis Mak. 2019 Oct 28;19(1):203. doi: 10.1186/s12911-019-0912-y.
5
Fertility preservation for transgender adolescents and young adults: a systematic review. transgender 青少年和年轻人的生育力保存：系统评价。
Hum Reprod Update. 2019 Nov 5;25(6):694-716. doi: 10.1093/humupd/dmz026.
6
Patterns of Fertility Discussions and Referrals for Youth at an Interdisciplinary Gender Clinic.跨学科性别诊所中青少年生育讨论和转介模式。
LGBT Health. 2019 Nov/Dec;6(8):417-421. doi: 10.1089/lgbt.2019.0076. Epub 2019 Oct 17.
7
Fertility Preservation in Children and Adolescents With Cancer: Pilot of a Decision Aid for Parents of Children and Adolescents With Cancer.癌症患儿及青少年的生育力保存：针对癌症患儿及青少年父母的决策辅助工具试点项目
JMIR Pediatr Parent. 2018 Nov 28;1(2):e10463. doi: 10.2196/10463.
8
Factors Affecting Fertility Decision-Making Among Transgender Adolescents and Young Adults.影响跨性别青少年和青年生育决策的因素。
LGBT Health. 2019 Apr;6(3):107-115. doi: 10.1089/lgbt.2018.0250.
9
Fertility preservation options for transgender and gender-nonconforming individuals. transgender 和 gender-nonconforming 个体的生育力保存选择。
Curr Opin Obstet Gynecol. 2019 Jun;31(3):170-176. doi: 10.1097/GCO.0000000000000537.
10
Knowledge, Practice Behaviors, and Perceived Barriers to Fertility Care Among Providers of Transgender Healthcare.跨性别医疗保健提供者的生育护理知识、实践行为和感知障碍。
J Adolesc Health. 2019 Feb;64(2):226-234. doi: 10.1016/j.jadohealth.2018.08.025. Epub 2018 Oct 26.

生育决策辅助工具在跨性别青少年和年轻成人中形成性发展的多学科德尔菲共识研究。

Formative development of a fertility decision aid for transgender adolescents and young adults: a multidisciplinary Delphi consensus study.

机构信息

Potocsnak Family Division of Adolescent and Young Adult Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, 225 East Chicago Avenue, Box 161B, Chicago, IL, 60611-2605, USA.

Department of Medical Ethics and Health Policy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

出版信息

J Assist Reprod Genet. 2020 Nov;37(11):2805-2816. doi: 10.1007/s10815-020-01947-8. Epub 2020 Sep 30.

DOI:10.1007/s10815-020-01947-8
PMID:32995972
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7642002/
Abstract

PURPOSE

No educational and decision support tools exist to aid transgender and non-binary (TNB) adolescents and young adults (AYA) in making decisions about fertility preservation in the context of initiating gender-affirming medical care that can impair fertility. This study identified critical content areas and learning objectives to include in a decision aid about fertility preservation targeted for TNB AYA.

METHODS

Delphi methodology was leveraged to engage 80 multidisciplinary experts in reproductive medicine and pediatric transgender health care in a two round consensus building procedure. Proposed content areas rated as "probably keep" or "definitely keep" by 75% of experts were retained. Proposed learning objectives reaching 75% agreement on ratings of importance and priority were also identified.

RESULTS

The Delphi procedure identified five priority content areas (Basic Reproduction; Gender-Affirming Medical Interventions: Impacts on Fertility; Established Fertility Preservation Options; Benefits and Risks of Established Fertility Preservation Procedures; Alternative Pathways to Parenting) and 25 learning objectives to prioritize in a fertility-related decision aid for TNB AYA.

CONCLUSION

A multidisciplinary panel of experts achieved agreement around content areas and learning objectives to incorporate into a decision aid about fertility preservation for TNB AYA.

摘要

目的

在开始性别肯定医疗护理以损害生育能力的情况下，没有教育和决策支持工具可以帮助跨性别和非二进制（TNB）青少年和年轻人（AYA）做出关于生育力保存的决策。本研究确定了关键的内容领域和学习目标，以纳入针对 TNB AYA 的生育力保存决策辅助工具。

方法

德尔菲法被用来在两个轮次的共识建立过程中，让 80 名来自生殖医学和儿科跨性别保健的多学科专家参与。被 75%的专家评为“可能保留”或“肯定保留”的拟议内容领域被保留。对重要性和优先级评分达成 75%一致的拟议学习目标也被确定。

结果

德尔菲程序确定了五个优先内容领域（基本生殖；性别肯定医疗干预：对生育能力的影响；已确立的生育力保存选择；已确立的生育力保存程序的益处和风险；育儿的替代途径）和 25 个学习目标，以优先考虑为 TNB AYA 制定生育相关决策辅助工具。

结论

一个多学科的专家小组就纳入 TNB AYA 生育力保存决策辅助工具的内容领域和学习目标达成了一致。