Rúbio Guilherme M D M, Keppler Bernhard K, Chin Jia Min, Reithofer Michael R
Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Strasse 42, 1090, Vienna, Austria.
Institute of Physical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Strasse 42, 1090, Vienna, Austria.
Chemistry. 2020 Dec 4;26(68):15859-15862. doi: 10.1002/chem.202003679. Epub 2020 Nov 18.
N-heterocyclic carbenes (NHCs) have received significant attention as gold nanoparticle stabilizers due to their strong binding affinity towards gold. However, their tunability is limited by the difficulty in obtaining nonsymmetric NHCs. In this regard, N-acyclic carbenes (NACs) are attractive alternatives due to their high synthetic versatility, allowing easy tuning of their steric and electronic properties towards specific applications. This work reports the first series of stable and monodisperse NAC-functionalized gold nanoparticles. These particles with sizes ranging 3.8 to 11.6 nm were characterized using NMR, UV/Vis and TEM. The nanoparticles display good stability at elevated temperatures and for extended periods both dried or dispersed in a medium, as well as in the presence of exogenous thiols. Importantly, these NAC-stabilized gold nanoparticles offer a promising and versatile alternative to NHC-stabilized gold nanoparticles.
N-杂环卡宾（NHCs）因其对金具有很强的结合亲和力，作为金纳米颗粒稳定剂受到了广泛关注。然而，由于难以获得非对称NHCs，其可调性受到限制。在这方面，N-无环卡宾（NACs）因其高度的合成通用性而成为有吸引力的替代物，能够轻松针对特定应用调节其空间和电子性质。这项工作报道了首个稳定且单分散的NAC功能化金纳米颗粒系列。使用核磁共振（NMR）、紫外/可见光谱（UV/Vis）和透射电子显微镜（TEM）对这些尺寸范围在3.8至11.6纳米的颗粒进行了表征。这些纳米颗粒在高温下以及长时间处于干燥或分散在介质中的状态下，甚至在存在外源硫醇的情况下，都表现出良好的稳定性。重要的是，这些NAC稳定的金纳米颗粒为NHC稳定的金纳米颗粒提供了一种有前景且通用的替代物。
