Šmejkalová Jindra, Borská Lenka, Hamáková Květa, Hodačová Lenka, Čermáková Eva, Fiala Zdeněk
Department of Hygiene and Preventive Medicine, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.
Department of Pathological Physiology, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.
Cent Eur J Public Health. 2020 Sep;28(3):219-225. doi: 10.21101/cejph.a5611.
The two main aims of our study were to assess the quality of life (QOL) of patients with moderate or severe psoriasis treated by Goeckerman therapy and to compare QOL of our patients on the date of admission and 1 month after their discharge.
We performed a prospective study on 51 patients treated for chronic plaque psoriasis by Goeckerman regimen (GR). The psoriasis area involvement and severity was measured using the Psoriasis Area and Severity Index (PASI). Patients' health-related QOL was evaluated using Psoriasis Disability Index (PDI).
In our study we demonstrated that the QOL of this sample of 51 patients with severe forms of psoriasis was relatively good; an average PDI value on the day of admission was 9.02, which represents a small effect on patient's QOL. We did not find any significant differences in QOL between younger and older respondents or between men and women. Despite good treatment efficiency, we did not find improvement in QOL 1 month after discharge.
The QOL of our patients was relatively good. This could be explained by the fact that our patients have been suffering from psoriasis for many years and have probably adapted to their disease. QOL of our patients was not directly dependent on the extent and intensity of skin changes. Further studies on the connection between psoriasis therapy and patients' QOL are still highly needed.
我们研究的两个主要目的是评估接受Goeckerman疗法治疗的中度或重度银屑病患者的生活质量(QOL),并比较我们的患者在入院时和出院后1个月的生活质量。
我们对51例接受Goeckerman方案(GR)治疗慢性斑块状银屑病的患者进行了一项前瞻性研究。使用银屑病面积和严重程度指数(PASI)测量银屑病面积累及程度和严重程度。使用银屑病残疾指数(PDI)评估患者与健康相关的生活质量。
在我们的研究中,我们证明了这51例重度银屑病患者样本的生活质量相对较好;入院当天的平均PDI值为9.02,这对患者的生活质量影响较小。我们没有发现年轻和年长受访者之间或男性和女性之间在生活质量上有任何显著差异。尽管治疗效果良好,但我们没有发现出院后1个月生活质量有改善。
我们患者的生活质量相对较好。这可能是因为我们的患者患有银屑病多年,可能已经适应了他们的疾病。我们患者的生活质量并不直接取决于皮肤变化的程度和强度。仍然非常需要对银屑病治疗与患者生活质量之间的联系进行进一步研究。