Jaworecka Kamila, Rzepko Marian, Marek-Józefowicz Luiza, Tamer Funda, Stefaniak Aleksandra A, Szczegielniak Magdalena, Chojnacka-Purpurowicz Joanna, Gulekon Ayla, Szepietowski Jacek C, Narbutt Joanna, Owczarczyk-Saczonek Agnieszka, Reich Adam
Department of Dermatology, Institute of Medical Sciences, Medical College of Rzeszow University, 35-310 Rzeszow, Poland.
Institute of Physical Culture Sciences, Medical College of Rzeszow University, 35-310 Rzeszow, Poland.
J Clin Med. 2022 Sep 22;11(19):5553. doi: 10.3390/jcm11195553.
Quality of life (QoL) and sleep, which are essential for well-being in the mental, physical, and socioeconomic domains, are impaired in psoriatic patients. However, the exact role of the clinical subtype of psoriasis in this aspect remains poorly studied.
The aim of this study was to investigate differences in QoL impairment and sleeping problems in patients suffering from various clinical subtypes of psoriasis and to evaluate the effects of pruritus on QoL.
This cross-sectional, multicenter study included 295 eligible subjects with diagnosed psoriasis. Each patient was examined with the use of the same questionnaire. Measures included predominant subtype of psoriasis, disease severity, pruritus scores, patients' health-related QoL and the incidence of sleep disturbance.
The QoL of most patients was decreased irrespectively of clinical psoriasis subtype, however, the most impaired QoL was in patients with erythrodermic psoriasis. The majority of patients reported sleep disturbances caused by pruritus, albeit there was no relevant differences between analyzed subgroups in this aspect of patients' well-being. Pruritus was an important factor determining QoL and sleeping problems in the studied population.
Identifying the most disturbing area of life and recognizing the most bothersome subjective symptoms of psoriasis are pivotal to focusing on the most relevant treatment goal and achieving therapeutic success.
生活质量（QoL）和睡眠对心理、身体及社会经济领域的幸福感至关重要，银屑病患者的生活质量和睡眠会受到损害。然而，银屑病临床亚型在这方面的确切作用仍研究不足。
本研究旨在调查不同临床亚型银屑病患者生活质量损害和睡眠问题的差异，并评估瘙痒对生活质量的影响。
这项横断面、多中心研究纳入了295名确诊为银屑病的合格受试者。每位患者均使用相同问卷进行检查。测量指标包括银屑病的主要亚型、疾病严重程度、瘙痒评分、患者的健康相关生活质量以及睡眠障碍发生率。
大多数患者的生活质量下降，与银屑病临床亚型无关，然而，红皮病型银屑病患者的生活质量受损最为严重。大多数患者报告瘙痒导致睡眠障碍，尽管在患者幸福感的这一方面，各分析亚组之间没有相关差异。瘙痒是决定所研究人群生活质量和睡眠问题的重要因素。
确定生活中最困扰的领域并认识到银屑病最烦人的主观症状，对于聚焦最相关的治疗目标并取得治疗成功至关重要。
