Department of Speech and Hearing Sciences, University of Washington, Seattle.
Am J Speech Lang Pathol. 2020 Nov 12;29(4):2145-2154. doi: 10.1044/2020_AJSLP-20-00058. Epub 2020 Sep 30.
Purpose The aim of this study was to examine whether acoustic dysarthria characteristics align with overall motor profile in individuals with Parkinson's disease (PD). Potential speech differences between tremor-dominant and non-tremor-dominant subtypes are theoretically motivated but empirically inconclusive. Method Twenty-seven individuals with dysarthria from PD provided a contextual speech sample. Participants were grouped into non-tremor-dominant ( = 12) and tremor-dominant ( = 15) motor subtypes according to the Unified Parkinson Disease Rating Scale. Dependent speech variables included fundamental frequency range, average pause duration, cepstral peak prominence, stuttering dysfluencies, and maze dysfluencies. Results There were no significant differences between the speech of the tremor-dominant and non-tremor-dominant groups. High within-group variability existed across parameters and motor subtypes. Conclusion Speech characteristics across the areas of phonation, prosody, and fluency did not differ appreciably between PD motor subtypes.
本研究旨在探讨帕金森病(PD)患者的构音障碍特征是否与整体运动特征相吻合。震颤优势和非震颤优势亚型之间的潜在言语差异具有理论依据,但尚无定论。方法:27 名患有构音障碍的 PD 患者提供了一段语境化的言语样本。根据统一帕金森病评定量表,参与者被分为非震颤优势(n=12)和震颤优势(n=15)运动亚型。依赖言语变量包括基频范围、平均停顿时间、倒谱峰突出度、口吃不流畅和迷宫不流畅。结果:震颤优势组和非震颤优势组的言语无显著差异。各参数和运动亚型内的组内变异性很高。结论:在发声、韵律和流畅性等方面,PD 运动亚型之间的言语特征没有明显差异。