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肝移植术后患者行开放式或腹腔镜网片修补切口疝:系统评价和比例荟萃分析。

Open or laparoscopic mesh repair of incisional hernia in patients that underwent liver transplantation: A systematic review and proportional meta-analysis.

机构信息

Laboratory of Experimental Surgery and Surgical Research "N. S. Christeas", National and Kapodistrian University of Athens, Athens, Greece.

1st Department of Propedeutic Surgery, Hippokration General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

出版信息

Clin Transplant. 2020 Dec;34(12):e14103. doi: 10.1111/ctr.14103. Epub 2020 Oct 14.

Abstract

BACKGROUND

Incisional hernias, that significantly affect the quality of life of patients, are common complications especially after major surgery, such as liver transplantation. The purpose of this meta-analysis is to outline the available evidence on the complications occurring after mesh implantation as a treatment of ventral incisional hernias (VIH) in liver transplant patients.

METHODS

MEDLINE, SCOPUS, Clinicaltrials.gov, CENTRAL and Google Scholar databases were searched for articles that reported the complications after mesh repair in patients that had undergone liver transplantation.

RESULTS

Eighteen studies, that involved 640 liver transplant patients who developed incisional hernia, were included. 546 of them underwent surgical repair with mesh implantation. 144 (26%) patients developed postoperative complications, and the most common was surgical site infection (17%). The pooled complication rate of open mesh repair of incisional hernia after liver transplantation was 23% (95% CI = 11%-37%), whereas the pooled complication rate of laparoscopic mesh repair was 20% (95% CI = 12%-29%).

CONCLUSION

Laparoscopic VIH repair with the implantation of mesh showed promising results, since the percentage of patients with postoperative complications was lower compared to the available data of those who underwent open VIH repair with mesh.

摘要

背景

切口疝是一种常见的并发症,尤其是在大型手术后,如肝移植后,会显著影响患者的生活质量。本荟萃分析的目的是概述在肝移植患者中使用网片治疗腹侧切口疝(VIH)后发生并发症的现有证据。

方法

在 MEDLINE、SCOPUS、Clinicaltrials.gov、CENTRAL 和 Google Scholar 数据库中检索了报道肝移植后网片修复后并发症的文章。

结果

纳入了 18 项研究,涉及 640 例发生切口疝的肝移植患者。其中 546 例接受了网片植入的手术修复。144 例(26%)患者发生术后并发症,最常见的是手术部位感染(17%)。肝移植后开放式网片修复切口疝的总体并发症发生率为 23%(95% CI=11%-37%),而腹腔镜网片修复的总体并发症发生率为 20%(95% CI=12%-29%)。

结论

与使用网片进行开放式 VIH 修复的可用数据相比,腹腔镜 VIH 修复并植入网片显示出有前景的结果,因为术后发生并发症的患者比例较低。

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