马来西亚基层医疗单位采用粪便潜血检测进行机会性结直肠癌筛检的 5 年评估。

A 5-year evaluation of using stool-based test for opportunistic colorectal cancer screening in primary health institutions across Malaysia.

机构信息

Cancer Unit, Disease Control Division, Ministry of Health, 62590 Putrajaya, Malaysia.

Clinical Research Center, Sultanah Bahiyah Hospital, 05460 Alor Setar, Kedah, Malaysia.

出版信息

Cancer Epidemiol. 2020 Dec;69:101829. doi: 10.1016/j.canep.2020.101829. Epub 2020 Sep 28.

DOI:10.1016/j.canep.2020.101829

PMID:32998070

Abstract

INTRODUCTION

The immunochemical fecal occult blood test (iFOBT) has been widely used for opportunistic colorectal cancer (CRC) screening in average-risk individuals seeking care from public health clinics in Malaysia. This study provides a 5-year outcome evaluation of such a practice.

METHODS

The findings for a few outcome indicators, ranging from the iFOBT uptake to the CRC and polyp detection rates, were generated from the data contributed by 583 public health clinics between 2014 and 2018. The trends in their changes were also evaluated.

RESULTS

The iFOBT uptake constantly increased over the years (p < 0.001), totaling 2.29 % (n = 127,957) as at 2018. Nearly 10 % (n = 11,872) of the individuals screened had a positive test result. Of those who underwent colonoscopy (n = 6,491), 4.04 % (n = 262) and 13.93 % (n = 904) were found to have CRC and polyps, respectively.

CONCLUSION

An uptrend in the CRC screening uptake was witnessed following the introduction of the iFOBT in public health clinics.

摘要

简介

免疫化学粪便潜血试验（iFOBT）已广泛应用于马来西亚公共卫生诊所就诊的普通风险人群的偶发性结直肠癌（CRC）筛查。本研究对这种做法进行了 5 年的结果评估。

方法

从 2014 年至 2018 年 583 家公共卫生诊所提供的数据中得出了一些结果指标的发现，包括 iFOBT 接受率、CRC 和息肉检出率。还评估了这些指标变化的趋势。

结果

iFOBT 的接受率多年来持续上升（p < 0.001），截至 2018 年总计为 2.29%（n = 127957）。近 10%（n = 11872）的筛查者检测结果呈阳性。在接受结肠镜检查的人群中（n = 6491），分别有 4.04%（n = 262）和 13.93%（n = 904）发现 CRC 和息肉。