School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan.
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Psychol Health. 2021 Sep;36(9):1102-1114. doi: 10.1080/08870446.2020.1825713. Epub 2020 Sep 30.
The present study examined the potential mediating influences of meaning in life and quality of life in the relationship of trait mindfulness and depressive symptoms in lung cancer patients. We adopted a cross-sectional design studying a sample of patients with non-small cell lung cancer, aged 20-65 years, and receiving cancer treatments or follow-up care. The outcome measures included Beck Depression Inventory-II, European Organisation for Research and Treatment of Cancer Core Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and lung cancer specific complementary measure (EORTC QLQ-LC13), Five Facet Mindfulness Questionnaire, and the meaning in life questionnaire. Among 116 lung cancer patients, 26.72% of them had clinically significant depressive symptoms. The presence of meaning, quality of life (QOL) functioning and symptom distress mediated the relationship of trait mindfulness and depressive symptoms. Multiple mediation analyses found that the presence of meaning in life was the main mediator. The reductions of depressive symptoms might be related to trait mindfulness enhancing lung cancer patients' perceptions of meaning in life. A mindfulness program has the potential to improve depressive symptoms in people with lung cancer.
本研究旨在探讨生活意义和生活质量在特质正念与肺癌患者抑郁症状关系中的中介作用。我们采用横断面设计，研究了年龄在 20-65 岁之间、正在接受癌症治疗或随访的非小细胞肺癌患者样本。研究结果包括贝克抑郁量表第二版、欧洲癌症研究与治疗组织核心癌症生活质量问卷（EORTC QLQ-C30）和肺癌特定补充措施（EORTC QLQ-LC13）、五因素正念量表和生活意义问卷。在 116 名肺癌患者中，26.72%的患者存在临床显著的抑郁症状。生活意义、生活质量（QOL）功能和症状困扰的存在中介了特质正念和抑郁症状之间的关系。多项中介分析发现，生活意义的存在是主要的中介因素。抑郁症状的减轻可能与特质正念增强了肺癌患者对生活意义的感知有关。正念训练有可能改善肺癌患者的抑郁症状。
