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骨水泥型与非骨水泥型全髋关节置换治疗老年股骨颈骨折:一项回顾性、多中心研究,平均随访 5 年。

Cemented versus uncemented total hip replacement for femoral neck fractures in elderly patients: a retrospective, multicentre study with a mean 5-year follow-up.

机构信息

Department of Hepatobiliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan 2nd Road, Yuexiu District, Guangzhou, 510080, China.

Department of Radiology, The First Affiliated Hospital, Sun Yat-sen University, No. 58, Zhongshan 2nd Road, Yuexiu District, Guangzhou, 510080, China.

出版信息

J Orthop Surg Res. 2020 Sep 30;15(1):447. doi: 10.1186/s13018-020-01980-4.

DOI:10.1186/s13018-020-01980-4
PMID:32998756
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7528391/
Abstract

BACKGROUND

Cemented or uncemented total hip replacement (CTR or UTR) for femoral neck fractures (AO/OTA type 31B/C) is a relatively common procedure in elderly individuals. The recent literature is limited regarding long-term outcomes following CTR versus UTR in the Asian population.

METHODS

Using our institutional database, we performed long-term outcome analysis on 268 patients with femoral neck fractures (AO/OTA type 31B/C) who had undergone a primary UTR or CTR (CTR: n = 132, mean age, 67.43 ± 6.51 years; UTR: n = 136, mean age, 67.65 ± 6.13 years) during 2007-2014, and these patients were followed until 2019. Follow-up occurred 1, 3, 6, and 12 months postoperatively and yearly thereafter. The primary endpoint was the Harris hip score (HHS); the secondary endpoint was the incidence of orthopaedic complications.

RESULTS

The mean follow-up time was 62.5 months (range, 50.1-76.1 months). At the final follow-up, the HHS was 79.39 ± 16.92 vs 74.18 ± 17.55 (CTR vs UTR, respectively, p = 0.011). Between-group significant differences were observed regarding the incidence of prosthesis revision, prosthesis loosening, and periprosthetic fracture (7.6% [95% CI, 6.4-8.2] for CTR vs 16.9% [95% CI, 14.7-17.3] for UTR, p = 0.020; 9.8% [95% CI, 8.3-10.7] for CTR vs 19.9% [95% CI, 18.2-20.9] for UTR, p = 0.022; 5.3% [95% CI, 4.4-6.7] for CTR vs 13.2% [95% CI, 12.1-13.8] for UTR, p = 0.026, respectively).

CONCLUSION

CTR showed superiority to UTR by improving the HHS and decreasing the incidence of orthopaedic complications. Our findings need to be confirmed in a prospective, randomized controlled study to verify whether they can be applicable to a broader population.

摘要

背景

对于股骨颈骨折(AO/OTA 31B/C 型),骨水泥型或非骨水泥型全髋关节置换术(CTR 或 UTR)在老年患者中较为常见。目前,关于亚洲人群中 CTR 与 UTR 长期疗效的文献较为有限。

方法

我们使用机构数据库,对 2007 年至 2014 年间行初次 UTR 或 CTR(CTR:n=132,平均年龄 67.43±6.51 岁;UTR:n=136,平均年龄 67.65±6.13 岁)治疗的 268 例股骨颈骨折(AO/OTA 31B/C 型)患者进行了长期疗效分析,这些患者随访至 2019 年。术后 1、3、6 和 12 个月以及此后每年进行随访。主要终点为 Harris 髋关节评分(HHS);次要终点为骨科并发症的发生率。

结果

平均随访时间为 62.5 个月(50.1-76.1 个月)。末次随访时,HHS 为 79.39±16.92(CTR)和 74.18±17.55(UTR)(CTR 与 UTR 相比,p=0.011)。组间在假体翻修、假体松动和假体周围骨折的发生率方面存在显著差异(7.6%[95%CI,6.4-8.2] vs 16.9%[95%CI,14.7-17.3],p=0.020;9.8%[95%CI,8.3-10.7] vs 19.9%[95%CI,18.2-20.9],p=0.022;5.3%[95%CI,4.4-6.7] vs 13.2%[95%CI,12.1-13.8],p=0.026)。

结论

与 UTR 相比,CTR 可改善 HHS 并降低骨科并发症发生率,具有优势。需要前瞻性、随机对照研究来证实这些发现,以确定其是否适用于更广泛的人群。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/7528391/dc06b274696b/13018_2020_1980_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/7528391/4d4cc7e59abe/13018_2020_1980_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/7528391/0a103025024a/13018_2020_1980_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/7528391/a5d71fd327de/13018_2020_1980_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/7528391/dc06b274696b/13018_2020_1980_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/7528391/4d4cc7e59abe/13018_2020_1980_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/7528391/0a103025024a/13018_2020_1980_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/7528391/a5d71fd327de/13018_2020_1980_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/7528391/dc06b274696b/13018_2020_1980_Fig4_HTML.jpg

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