Berger G, Laugier P, Fink M, Perrin J
Ultrason Imaging. 1987 Jan;9(1):1-17. doi: 10.1177/016173468700900101.
This paper deals with the measurement of the attenuation of ultrasound in muscle and its application to the detection of Duchenne Muscular Dystrophy (DMD) carriers. The precision obtained when measuring the attenuation is an important parameter to be considered. A statistical approach is taken on simulated data and compared to in vivo results. The results allow discussion for the minimum tissue volume needed for the estimation. Variations in muscle attenuation between normals were obtained from studies on 27 volunteers. These attenuation values were compared to those obtained from 19 carriers of DMD. Attenuation appears to be a potential clinical indicator of DMD carriers.
本文探讨了超声在肌肉中的衰减测量及其在杜氏肌营养不良症（DMD）携带者检测中的应用。测量衰减时所获得的精度是一个需要考虑的重要参数。对模拟数据采用了统计方法并与体内结果进行了比较。这些结果有助于讨论估计所需的最小组织体积。通过对27名志愿者的研究获得了正常个体之间肌肉衰减的变化情况。将这些衰减值与19名DMD携带者所获得的衰减值进行了比较。衰减似乎是DMD携带者的一个潜在临床指标。
